High Throughput Screening
Humana Press Inc. (Verlag)
978-0-89603-889-9 (ISBN)
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In "High Throughput Screening", leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wish had been available when they started in HTS, these expert seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge.
Design and Implementation of High Throughput Screening Assays Ricardo Macarron and Robert P. Hertzberg Configuring Radioligand Receptor Binding Assays for HTS Using Scintillation Proximity Assay Technology John W. Carpenter, Carmen Laethem, Frederick R. Hubbard, Thomas K. Eckols, Melvyn Baez, Don McClure, David L. G. Nelson, and Paul A. Johnston Homogeneous Techniques for Monitoring Receptor-Ligand Interactions James S. Marks, Douglas S. Burdette, and David A. Giegel Comparison of SPA, FRET, and FP for Kinase Assays Jinzi J. Wu Electrochemiluminescence: A Technology Evaluation and Assay Reformatting of the Stat6/P578 Protein-Peptide Interaction Robert H. Schweitzer and Laura Abriola Cellular Assays in HTS Patricia Johnston Compound Library Management James A. Chan and Juan A. Hueso-Rodriguez Compound Library Management: An Overview of an Automated System Wilma W. Keighley and Terry P. Wood Natural Products or Not? How to Screen for Natural Products in the Emerging HTS Paradigm Susan P. Manly, Ramesh Padmanabha, and Susan E. Lowe Introduction to Screening Automation Steven Hamilton Unit Automation in High Throughput Screening Karl C. Menke Fully Automated Screening Systems Seth Cohen and Robert F. Trinka Management and Maintenance of High Throughput Screening Systems Barbara Hynd
| Erscheint lt. Verlag | 18.4.2002 |
|---|---|
| Reihe/Serie | Methods in Molecular Biology ; v. 190 |
| Zusatzinfo | 55 black & white illustrations, 5 colour illustrations, 4 black & white halftones, 51 black & white line drawings |
| Verlagsort | Totowa, NJ |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 1 g |
| Einbandart | gebunden |
| Themenwelt | Medizin / Pharmazie ► Pharmazie |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 0-89603-889-0 / 0896038890 |
| ISBN-13 | 978-0-89603-889-9 / 9780896038899 |
| Zustand | Neuware |
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