Malaria

Maria M. Mota, Instituto de Medicina Molecular, Lisbon, Portugal

Part I. Immune Response to Infection.- Innate Immunity to Malaria.- Mechanisms of Adaptive Immunity to Plasmodium Liver-Stage Infection: The Known and Unknown.- Adaptive Immunity to Blood Stages.- Pathogenetic Immune Responses in Cerebral Malaria.- A Role for Autoimmunity in the Immune Response Against Malaria.- Part II. Immune Response to Malaria Vaccines - Liver Stage Vaccines.- Whole-Sporozoite Malaria Vaccines.- Immune Responses to the RTS,S/AS01 Malaria Vaccine Candidate: Lessons from Human Immunology, Parasitologic and Clinical Evaluations.- Viral Vector Vaccines for Liver Stage Malaria.- Epitopic Malaria Vaccines Comprised of Minimal T and B cell Epitopes of the P. falciparum CS Protein.- Part III. Immune Response to Malaria Vaccines - Blood Stage Vaccines.- Immune Responses to Whole Organism Blood-Stage Malaria Vaccines.- Subunit Vaccines.- Part IV. Immune Response to Malaria Vaccines - Transmission Blocking Vaccines.- Antimalarial Transmission Blocking Vaccines.

"This book will be an excellent resource for established malaria investigators interested in a broad look at the overall malaria vaccine effort. As well, the book will provide an excellent opportunity for new investigators entering the malaria field, including students and fellows, to quickly establish a relevant base of knowledge. ... The authors deliver a well-written, excellent review of the state of the field that integrates basic studies of immune responses with applied aspects of vaccine development." (James M. Burns, Doody's Book Reviews, May, 2017)