Essentials of Spine Biologics

Wellington K. Hsu, MD is the Clifford C. Raisbeck Distinguished Professor of Orthopaedic Surgery at Northwestern University Feinberg School of Medicine in Chicago, Illinois, USA. At Northwestern, Dr. Hsu heads the Laboratory for Regenerative Technologies where his research focuses on tissue engineering and bone graft substitutes for spinal fusion. Dr. Hsu is also Director of the Professional Athlete's Spine Initiative, which retrospectively studies clinical outcomes in elite professional athletes after spine surgery. He has been widely interviewed for his expertise in outcomes of high-performance athletes is recognized as a Top 10 Spine Surgeon in Biologics Research.

Introduction. Principles of Tissue Regeneration in the Spine. Bony Fusion. Disc Regeneration. Nerve Regeneration. Bony Fusion. Anatomic Location and Mechanisms. Classification of Products. Potential Complications. Degenerative Disc Disease. Indications: Difficulty of Diagnosis and Placebo Effect. Improvement of Pain Versus Advanced Imaging. Classification of Products. Spinal Cord Injury (Nerve Root Regeneration). Neuroprotective versus Neuroregenerative Approaches. Classification of Products. Promising Advances On the Horizon.