Brain and Spinal Tumors of Childhood

David A. Walker is Professor Paediatric Oncology, School of Medicine, University of Nottingham, Nottingham, UK Giorgio Perilongo is Director, Department of Woman’s and Child’s Health, Division of Pediatrics, University of Padua, Padua, Italy Roger E. Taylor is Professor of Clinical Oncology, College of Medicine, Swansea University; Honorary Consultant Clinical Oncologist, South West Wales Cancer Centre, Singleton Hospital, Swansea, UK Ian F. Pollack is Chief, Pediatric Neurosurgery, Children's Hospital of Pittsburgh, Leland Albright Distinguished Professor of Neurological Surgery, Vice Chairman for Academic Affairs, Department of Neurological Surgery, Co-Director, UPCI Brain Tumor Program, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

List of Contributors. Introduction. Epidemiology of Childhood Brain Tumors. Clinical Presentation and Associated Syndromes of Brain Tumor. Pediatric Central Nervous System Tumors as Phenotypic Manifestation of Cancer Predisposition Syndromes. Anatomical and Biological Imaging of Pediatric Brain Tumor. Neurosurgical Techniques and Strategies. Radiotherapy for Pediatric Central Nervous System Tumors – Techniques and Strategies. Physical and Cognitive Rehabilitation for Children with Brain and Spinal Tumors. Drug Delivery. Low-grade Glioma Presenting in the Optic Pathways and Hypothalamus (NF1. and Sporadic). Low-grade Glioma: Principles of Diagnosis and Drug Treatment. High-grade Glioma. Diffuse Intrinsic Pontine Glioma. Embryonal Tumors. Ependymoma in Childhood and Adolescence. Germ Cell Tumors of the Central Nervous System. Atypical Teratoid / Rhabdoid Tumors – AT/ RT. Craniopharyngioma. Choroid Plexus Tumors and Meningiomas. Pediatric Spinal Tumors. Late Effects of Treatment for Childhood Brain and Spinal Tumors. The Power of Patient Advocacy in Pediatric Neuro-oncology. Index