Chemical Biology of Human Vitamins

Prof Walsh was on the faculty of MIT and Harvard Medical School and is now affiliated with the ChEM-H Institute at Stanford University.  Yi Tang is a professor of Chemical and Biochemical Engineering, and Chemistry at UCLA. Between them they have published many research and review articles that examine  the chemical logic that underlies both  primary and secondary metabolic pathways. Among their joint efforts is the recent monograph Natural Product Biosynthesis, Chemical Logic and Enzymatic Machinery (Royal Society of Chemistry, 2017).

Section 1: Overview, A Molecular View of Vitamin Action;

Human Vitamins: Discovery and Characterization;

Metabolic Logic through the Lens of Coenzyme Forms of Human Vitamins;

Section 2: The Metabolic Roles of Water-soluble Vitamins;

Vitamin B1 Converted to the Coenzyme Thiamin Pyrophosphate;

Vitamin B2 Riboflavin;

Vitamin B3 Niacin and the Nicotinamide Coenzymes;

Vitamin B5: Pantothenate;

Coenzyme Forms of Vitamin B6;

Vitamin B7: Biotin;

Vitamin B9: Folic Acid;

Vitamin B12: Two Coenzyme Forms;

Vitamin C: Ascorbic Acid;

Section 3: The Metabolic Roles of Lipid-soluble Vitamins;

Vitamin A: Three Vitamer Forms: Retinol, Retinal, and Retinoic Acid;

Vitamin D;

Vitamin E;

Vitamin K;

Section 4;

Vitamin Chemistry Drives Human Metabolic Logic;

Subject Index