Hepatocyte and Kupffer Cell Interactions (1992)

Timothy R. Billiar, M.D., has served as the George Vance Foster Professor and Chair in the Department of Surgery at the University of Pittsburgh School of Medicine since 1999. Dr. Billiar completed his surgical residency at the University of Minnesota and the University of Pittsburgh. Dr. Billiar's research has also been recognized with membership in the Institute of Medicine and the National Academy of Sciences. Education BA Natural Sciences, Doane College, NE MD Medicine, University of Chicago, Pritzker School of Medicine Dr. Curran graduated from the Rush Medical College in 1984. He works in Chicago, IL and specializes in Cardiovascular Disease and General Surgery . Dr. Curran is affiliated with Swedish Covenant Hospital. He speaks English and Korean. Education & Training Medical School: graduated from the Rush Medical College Graduation Date: in 1984. Specialties & Hospital Affiliations Hospital Affiliations: Swedish Covenant Hospital Specialties: Cardiovascular Disease and General Surgery

Section 1 - The Normal Liver: 1. The Origin of Kupffer Cells and Their Anatomic Relationship to Hepatocytes 2. Modes of Communication between Kupffer Cells and Hepatocytes Under Normal and Pathological Conditions 3. Experimental Models for Studying the Interaction of Kupffer Cells and Hepatocytes Section 2 - Nonseptic pathologic States: 4. Antitumor Defense System of the Liver 5. Alcohol-Induced Liver Disease 6. Viral Infections and Hepatitis 7. Role of Macrophages and Endothelial Cells in Hepatotoxicity 8. Liver Alloimmunity 9. Nonparenchymal Cell and Hepatocyte Interaction in Antimalarial Activity: A Central Role for Nitric Oxide Section 3 - The Liver in Sepsis: 10. Regulation of Kupffer Cell Activation 11. The Role of Kupffer Cells in Control of Acute Phase Protein Synthesis 12. The Changes in Hepatic Lipid and Carbohydrate Metabolism in Sepsis