Chronic Lymphocytic Leukemia

Ex-Vivo signal Transduction Studies in Chronic Lymphocytic Leukemia.- Ex vivo Pharmacological Profiling in Chronic Lymphocytic Leukemia Cells.- Culture and Harvest of CpG-stimulated Blood and Bone Marrow in Chronic Lymphocytic Leukemia.- Analysis of Common Abnormalities seen in Chronic Lymphocytic Leukemia using Fluorescence in situ Hybridization.- Immunoglobulin Gene Analysis in Chronic Lymphocytic Leukemia.- Detection and Functional Analysis of TP53 Mutations in CLL.- The Development and Use of Scalable Systems for Studying Aberrant Splicing in SF3B1-mutant CLL.- Methods for Investigating VLA-4 (CD49d/CD29) Expression and Activation in Chronic Lymphocytic Leukemia and its Clinical Applications.- In vitro Assay to Study CLL and Monocyte Interactions.- Extracellular Flux Assays to Determine Oxidative Phosphorylation and Glycolysis in Chronic Lymphocytic Leukemia Cells.- Measurement of Leukemic B-cell Growth Kinetics in Patients with Chronic Lymphocytic Leukemia.- Assays on DNA Damage and Repair in CLL.- Method for Generating a Patient-Derived Xenograft Model of CLL.- Immunological Methods to Study Monoclonal Antibody Activity in Chronic Lymphocytic Leukemia.- CRISPR/Cas9-based Gene Dropout Screens.- Gene Disruption using CRISPR-Cas9 Technology.- Minimal Residual Disease Quantification in Chronic Lymphocytic Leukemia: Clinical Significance and Flow Cytometric Methods.- Rare Variant Quantitation Using Droplet Digital PCR.- Methods for Measuring ctDNA in Lymphomas.- Measurement of miRNAs in Chronic Lymphocytic Leukemia Patient Samples by Quantitative Reverse Transcription PCR.- Bioinformatics Analysis of Whole Exome Sequencing Data.- Genome Sequencing and Analysis Methods in Chronic Lymphocytic Leukemia.- Characterization of Somatically-acquired Copy Number Alterations in Chronic Lymphocytic Leukaemia using Shallow Whole Genome Sequencing.- High-throughput Sequencing of the T Cell Receptor Beta Chain Gene Repertoire in Chronic Lymphocytic Leukemia.