Practical Guide to Transcranial Direct Current Stimulation

Helena Knotkova, PhD, PhilD Director of Clinical Research and Analytics MJHS Institute for Innovation in Palliative Care Associate Professor Department of Family and Social Medicine Albert Einstein College of Medicine New York, New York, USA

tDCS among technologies for low-intensity transcranial electrical stimulation.- Principles of tDCS.- Mechanisms of acute effects and after effects.- Current methods and approaches in tDCS.-  tDCS modulation of neurophysiological functional outcomes.- Safety measures.- Methodological considerations for selection of tDCS approach, protocol and device.- Stimulation parameters and their interaction.- Role of computational modeling for dose determination.- Preparation, placement, methods for electrode-position determination.- Monitoring of physiological effects and functional outcomes.- tDCS integration with MRI, EEG, and fNIRS.- Methodological considerations for tDCS in clinical trials.- Specifics of home-based patient-delivered remotely-supervised tDCS.- tDCS ethics and professional conduct.- tDCS in psychiatry.- tDCS for functional enhancement and symptom control in neurodegenerative diseases.- tDCS in Post-stroke rehabilitation.- tDCS potential for pain management.- tDCS in aging.- tDCS in cognitive neuroscience.- Challenges, open questions and future direction in tDCS research and applications.