Regenerative Strategies for Maxillary and Mandibular Reconstruction

James C. Melville, DDS, FACS, is Assistant Professor of Surgery in the Department of Oral and Maxillofacial Surgery, Oral, Head & Neck Oncology and Reconstructive Surgery at The University of Texas Health Science Center at Houston, Houston, Texas, USA. He graduated from the University of Michigan School of Dentistry, Ann Arbor, MI, in 2005 and subsequently completed a General Practice Residency at the University of California San Francisco (UCSF) in 2006 and was appointed and served as an Assistant Professor until 2007. He completed a residency in Oral and Maxillofacial Surgery in 2012 and then a Fellowship in Oral, Head & Neck Oncology and Microvascular Reconstructive Surgery at the University of Miami/Jackson Memorial Hospital. Dr. Melville is a Diplomate of the American Board of Oral and Maxillofacial Surgery and a Fellow of the American Association of Oral & Maxillofacial Surgeons, American Academy of Craniomaxillofacial Surgeons, and American College of Surgeons. He has currently contributed to 6 chapters in major Oral & Maxillofacial Surgery and Tissue Engineering textbooks and is the author of more than 12articles in peer-reviewed journals. He acts as a reviewer for the Journal of Oral and Maxillofacial Surgery and Triple OOOO journal. Jonathan Shum, DDS, MD, FACS, FRCD(C), is Associate Professor at the University of Texas Health Science Center, Department of Oral and Maxillofacial Surgery as well as the Fellowship director of Oral, Head & Neck Oncology and Microvascular Surgery. He gained his Doctor of Dental Surgery at the University of Toronto, Canada, in 2005 and his Doctor of Medicine at Weill Cornell Medical College, New York, in 2010. In 2011 he completed the Oral and Maxillofacial Surgery Residency Program at New York Presbyterian Hospital of Cornell, and he has since completed fellowships in Head and Neck Oncology and Microvascular Reconstructive Surgery (Head and Neck Surgical Associates, Providence Portland Medical Center) and Maxillofacial Oncology and Microvascular Reconstructive Surgery (University of Maryland Medical Center/R Adams Cowley Shock Trauma Center, Baltimore). He is a fellow of the American College of Surgeons (2015) and the Royal College of Dentists of Canada (2016). He acts as a reviewer for several leading journals in the field. He is on the editorial board of Triple OOOO Journal.

Regenerative Medicine and the role of tissue engineering in Maxillomandibular reconstruction: Principles of Regenerative Medicine of the Maxillomandibular Region.- Traditional use of autogenous and allogeneic grafts in the head and neck reconstruction. Principles of bone grafting.- Reconstruction considerations for the post traumatic, benign tumor, and Oncologic patient.- The role of rh-BMP2 in maxillofacial reconstruction.- The role of autogenous growth factors in regenerative maxillofacial surgery (BMAC, PRP, PRF).- Techniques of obtaining BMAC, PRP, PRF.- Principles of skin and mucosa regeneration with bioengineering. Surgical Techniques utilizing Biotechnology for regeneration and reconstruction: Principles and technique of Mandibular Reconstruction with in-situ tissue engineering.- Tissue engineering techniques for atrophic maxilla and mandibles..- Maxillary Sinus Augmentation with tissue engineering.- Maxillary reconstruction with tissue engineering.- Use of tissueengineering in Dental implantology and dentalalveolar surgery.- Alveolar Ridge Augmentation (Vertical and Horizontal) with bioengineering. Tissue engineering for Transoral Procedures.- Current modalities of maxillofacial nerve regeneration, reconstruction and repair with allogeneic grafts.- Use of allogeneic dermal substitutes for maxillofacial reconstruction (Alloderm, Acell, Integra, etc). State of the art free vascular transfer for maxillomandibular reconstruction: Principles of Maxillary Reconstruction with vascularized flaps.- Principles of Mandibular Reconstruction with vascularized flaps.- Principles of a Jaw in a day (Free Fibula with immediate implants).- Role of Microvascular Free flaps combined with tissue engineering. Future trends for maxillomandibular regeneration and reconstruction: The application of 3D printing for reconstruction of maxillofacial defects.- Future of bioengineering for head and neck reconstruction: The customized free flap.