Targeted Drug Delivery

Synthesis of Cationic Polymer Libraries for Gene Delivery using Diglycidyl Ethers.- Generation of Ultra-Small PLGA Nanoparticles by Sequential Centrifugation.- Construction of Bacteria-Based Cargo Carriers for Targeted Cancer Therapy.- Production of Extracellular Vesicles Loaded with Therapeutic Cargo.- Delivery of Cytotoxic Mesenchymal Stem Cells with Biodegradable Scaffolds for Treatment of Postoperative Brain Cancer.- Nanoparticles for Targeted Drug Delivery to Cancer Stem-Like Cells and Tumor.- Exploiting Phage Display for Development of Novel Cellular Targeting Strategies.- CD44 Targeted Lipid Nanoparticles for MicroRNA Therapy.- Ultrasound and Microbubble-Mediated Blood-Brain Barrier Disruption for Targeted Delivery of Therapeutics to the Brain.- In Vitro Validation of Targeting and Comparison to Mathematical Modeling.- Enzyme-Linked Immunosorbent Assay to Quantify Targeting Molecules on Nanoparticles.- Tunable CollagenMicrofluidic Platform to Study Nanoparticle Transport in the Tumor Microenvironment.- Utilizing the Lung as a Model to Study Nanoparticle Based Drug Delivery Systems.- Non-Enzymatic Tissue Homogenization for Biodistribution Analysis.- Methods and Study Designs for Characterizing the Pharmacokinetics and Pharmacodynamics of Carrier-Mediated Agents.