Myotonic Dystrophy
Springer Verlag, Singapore
978-981-13-0507-8 (ISBN)
The book introduces readers to the molecular mechanisms within each organ and the resultant clinical features, which are presented together. In particular, it focuses on the central nervous system, since the pathology of the brain (central nervous system manifestation) has rarely been addressed systematically and will pose a persistent challenge, even if therapies have greatly advanced in the future. In addition, the book addresses the latest developments, such as research using patient-derived iPS cells and therapeutic research.
Myotonic Dystrophy provides essential information for neurologists and researchers with an interest in muscle disease, including muscular dystrophy. Furthermore, since the disease involves various complications of the brain, heart, metabolism, etc., the book will be of great value to clinicians and researchers in the cardiovascular sciences, endocrinology, diabetes, dementia, and neuropsychology, as well as genetic specialists.
Masanori P. Takahashi, M.D., Ph.D. Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine, Japan Tsuyoshi Matsumura, M.D., Ph.D. Department of Neurology, National Hospital Organization Toneyama National Hospital, Japan
Genetics of myotonic dystrophy (including cDM and DM2).- Basic Molecular pathomechanism.- Clinical features in skeletal muscle and their underlying molecular mechanism.- Clinical features in heart and their underlying molecular mechanism.- Clinical features of central nervous system.- Pathological changes in DM brain.- Molecular defect in DM central nervous system.- Respiratory feature in DM.- Glucose intolerance in DM.- Lipid metabolism in DM.- Dysphagia in DM.- DM patient-derived iPS cells.- Therapeutic development in DM.
Erscheinungsdatum | 21.09.2018 |
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Zusatzinfo | 42 Illustrations, color; 16 Illustrations, black and white; VIII, 214 p. 58 illus., 42 illus. in color. |
Verlagsort | Singapore |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie | |
Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
ISBN-10 | 981-13-0507-2 / 9811305072 |
ISBN-13 | 978-981-13-0507-8 / 9789811305078 |
Zustand | Neuware |
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