Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs (eBook)

Cell Signaling Pathways and microRNAs in Cancer Biology
eBook Download: PDF
2018 | 1st ed. 2018
XII, 308 Seiten
Springer International Publishing (Verlag)
978-3-319-71553-7 (ISBN)

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Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs -
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Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics.

This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.


Sundas Fayyaz is working as a Scientist in research laboratory of Rashid Latif Medical College (RLMC). Her expertise lies in cancer genetics and therapeutics. 

Ammad Ahmad Farooqi is currently a Senior Scientist at the Institute of Biomedical and Genetic Engineering (IBGE), in Islamabad, Pakistan. His area of research is tightly focused on cancer genetics and therapeutics.

Sundas Fayyaz is working as a Scientist in research laboratory of Rashid Latif Medical College (RLMC). Her expertise lies in cancer genetics and therapeutics. Ammad Ahmad Farooqi is currently a Senior Scientist at the Institute of Biomedical and Genetic Engineering (IBGE), in Islamabad, Pakistan. His area of research is tightly focused on cancer genetics and therapeutics.

1. From Endometriosis to Cancer: Spotlight on Intracellular Signaling Cascades and MicroRNAs2. Tyrosine kinases, microRNAs, epigenetics: new insights in the mechanisms of leukemogenesis3. The emerging role of exosomes in cancer progression and their potential as therapy targets4. Tranquilizing and Awakening ATM to Promote Killing of Cancer Cells5. The Role of GPER Signaling in Carcinogenesis: a Focus on Prostate Cancer6. Bone Cancer: Dysregulation of Signaling Cascades by microRNAs7. The roles of miR-25 and its targeted genes in human cancer8. Notch Signaling in Lung Cancer Initiation and Development9. TGF-β/Smad signalling pathway in cancer10. Natural Agents Mediated Regulation of microRNAs: Do We Need Skilled Archers to Hit the Bullseye11. Sebaceous Carcinoma of the Eyelid12. Current knowledge of miRNAs as biomarkers in Breast Cancer13. Signaling Landscape of AML: The Story So Far14. When the molecules start playing chess, or how microRNAs acquire dualistic activity during cancer progression15. The Crosstalk Between miRNAs and Autophagy in Cancer Progression16. Role of CEACAM in Different CancersIndex

Erscheint lt. Verlag 7.3.2018
Zusatzinfo XII, 308 p. 16 illus. in color.
Verlagsort Cham
Sprache englisch
Themenwelt Medizin / Pharmazie Studium
Schlagworte Cancer Development and Progression • microRNA • molecular oncology • Signaling cascades • signal transduction
ISBN-10 3-319-71553-4 / 3319715534
ISBN-13 978-3-319-71553-7 / 9783319715537
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