Etiology of Breast and Gynecological Cancers

Toward a unified concept of mammary carcinogenesis; epidemiologic analysis of breast and gynaecologic cancers; recent advances in the molecular genetics of hereditary breast and ovarian cancer; defining etiologic heterogeneity in breast cancer using genetic biomarkers; the genetics of sporadic breast cancer; molecular epidemiology of breast cancer; molecular perspectives on cancer, the cell cycle and the inherited disorder ataxia-telangiectasi; radiation and breast cancer risk; genotoxicity of environmental agents in human mammary epithelial cells - a trigger for human breast cancer; organochlorine exposure and risk for breast cancer; diet and breast cancer - opportunities for prevention and intervention; perspectives and progress in development of breast cancer chemopreventive drugs; the molecular genetics of endometrial carcinoma; rodent model of reproductive tract leiomyomata - characterization and use in preclinical therapeutic studies; mechanisms of DES carcinogenicity - effects of the TGF (transgene); estrogens and the genetic control of tumour growth; targeted antiestrogens; the metabolism and genotoxicity of tamoxifen; tamoxifen breast cancer prevention trial - an update.