Principles of Biostatistics

Marcello Pagano is Professor of Statistical Computing in the Department of Biostatistics at the Harvard School of Public Health. His research in biostatistics is on computer intensive inference and surveillance methods that involve screening methodologies, with their associated laboratory tests, and in obtaining more accurate testing results that use existing technologies. Kimberlee Gauvreau is Associate Professor in the Department of Biostatistics and Associate Professor of Pediatrics at Harvard Medical School. Dr. Gauvreau’s research focuses on biostatistical issues arising in the field of pediatric cardiology. She also works on the development and validation of methods of adjustment for case mix complexity.

1 Introduction

2 Data Presentation

3 Numerical Summary Measures

4 Rates and Standardization

5 Life Tables

6 Probability

7 Theoretical Probability Distributions

8 Sampling Distribution of the Mean

9 Confidence Intervals

10 Hypothesis Testing

11 Comparison of Two Means

12 Analysis of Variance

13 Nonparametric Methods

14 Inference on Proportions

15 Contingency Tables

16 Multiple 2 x 2 Tables

17 Correlation

18 Simple Linear Regression

19 Multiple Regression

20 Logistic Regression

21 Survival Analysis

22 Sampling Theory

Appendix A Tables

Appendix B Data Sets

Index