Ethical Issues in HIV Vaccine Trials
Palgrave Macmillan (Verlag)
978-0-333-67492-5 (ISBN)
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This work explores some of the complex ethical quandaries entailed by proposed phase III HIV preventive vaccine trials. It argues that such trials must be initiated as soon as is politically and ethically feasible on the one hand, and, on the other, that no such trials should be undertaken until we can assure full compliance with the Nuremberg Code and the WHO/CIOMS International Ethical Guidelines for Biomedical Research Involving Human Subjects. The tension between these two positions is documented, and suggestions offered for how to think about possible resolutions.
Preface - Introduction - Where Stands the Pandemic Now? - It's Not Just Another Disease - Will it Ever Slow Down? - Is a Vaccine Possible? - The Human Immunodeficiency Virus - How the Immune System Works - How Vaccines Work - Human Trials - Criteria of Effectiveness -Ethical Principles - Real Risks - Whom do You Want for Volunteers? - Compensating Volunteers for Injury - Informed Consent (1) - Assessing Comprehension - Informed Consent (2) - Ethics Review Committees - Protecting Individual Subjects - Proxy Consent? - Undue Inducement - Motivations to Volunteer - Still More Questions - Data from Unethical Experiments? - The Great Simple Solution - Thesis/Antithesis: Synthesis? - Smallpox and Guinea Worm Disease as Metaphors - So... - Appendix I: The Nuremberg Code - Appendix II: WHO/CIOMS International Ethical Guidelines - Appendix III: A Proposed Bill of Rights and Responsibilities - Appendix IV: A Test of Understanding for HIV Vaccine Trials - Appendix V: Application Forms for Ethical Review - Selected Bibliography - Notes - Index
| Erscheint lt. Verlag | 4.12.1996 |
|---|---|
| Zusatzinfo | tables, bibliography, index |
| Verlagsort | Basingstoke |
| Sprache | englisch |
| Maße | 138 x 216 mm |
| Gewicht | 363 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Medizinethik |
| Studium ► Querschnittsbereiche ► Geschichte / Ethik der Medizin | |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| Studium ► Querschnittsbereiche ► Prävention / Gesundheitsförderung | |
| ISBN-10 | 0-333-67492-8 / 0333674928 |
| ISBN-13 | 978-0-333-67492-5 / 9780333674925 |
| Zustand | Neuware |
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