Epinephrine in the Central Nervous System

HISTORICAL OVERVIEW: J Axelrod: Following the trail of epinephrine from the periphery to the brain; M Vogt: The changing face of research on epinephrine; MORPHOLOGY OF BRAIN EPINEPHRINE SYSTEMS: T Hokfelt and others: Central phenylethanolamine N-methyltransferase-immunoreactive neurons: Distribution, projections, fine structure, ontogeny and coexisting peptides; L F Agnati and others: Morphometric studies of epinephrine and neuropeptide Y (NPY) costoring neurons in the rat brain; J R Unnerstall & M J Kuhar: Mapping the alpha adrenergic receptor in the central nervous system: A guide to structure and function; M Kalia and others: Connectivity and ultrastructure of nonadrenergic and adrenergic neurons in the medulla oblongata; REGULATION AND GENETICS OF ADRENERGIC SYSTEMS: D J Loftus and others: Inheritance of epinephrine formation rates and phenylethanolamine N-methyltransferase structural heterology in inbred rat strains; M J Evinger and others: Molecular basis for the difference in buffalo and Fischer rat PNMT expression; K L Kelner and others: Steroid control of neurotransmitter synthesis: Glucocorticoid regulation of phenylethanolamine N-methyltransferase; J M Saavedra: Brain epinephrine in hypertension and stress; PHARMACOLOGICAL APPROACHES TO ADRENERGIC SYSTEMS: G L Grunewald and others: Approaches to the design of selective inhibitors of phenylethanolamine N-methyltransferase (PNMT): Development of an active site model for PNMT; B Renaud and others: Biochemical pharmacology of brain epinephrine neurons: Comparison with non-epinephrine neurons; L C Terry: Regulation of anterior pituitary hormone secretion by brain epinephrine; H-U Affolter & T Reisine: Epinephrine and CRF stimulate ACTH release and proopiomelanocortin gene expression; M Goldstein and others: Central epinephrine neurons and alpha-2 adrenoceptors; M Fujimoto, E Costa and others: Modulation of epinephrine release from adrenal medulla by gamma-aminobutyric acid; BRAIN AND PERIPHERAL ADRENOCEPTORS: D B Bylund: Subtypes of alpha-2 adrenoceptors in human and rat brain; P A Insel and others: Agonist-regulated metabolism of alpha- and beta-adrenoceptors; D C U'Prichard, D J Loftus & J M Stolk: Functional association between epinephrine neurons and alpha-2 adrenoceptors in discrete brain areas: analysis in inbred rat strains; C A Hamilton, C R Jones, N Deighton & J L Reid: Regulation of brain stem and platelet alpha-2 adrenoceptors; S N Abramson & P B Molinoff: The beta-adrenergic receptor-coupled adenylate cyclase system; S R Childers & S P Baker: Modification of guanine nucleotide actions on receptors and adenylate cyclase; R A Keith, B B Howe & A I Salama: Central and peripheral alpha-2 and beta adrenoceptor changes induced by antidepressant treatments; ADRENERGIC NEURON ELECTROPHYSIOLOGY AND BEHAVIOR: J T Williams, A Surprenant & R A North: Inhibitory synaptic transmission mediated by catecholamines; D N F