Vitiligo

Somesh Gupta, MD, DNB, MNAMS, Professor, Department of Dermatology & Venereology, All India Institute of Medical Sciences, New Delhi, India

Mats J. Olsson, MD, PhD, CEO, ParkCell AB and President, International Vitiligo Center, Uppsala, Sweden

Davinder Parsad, MD, Professor, Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education & Research, Chandigarh, India

Henry W. Lim, MD, Chair Emeritus, Department of Dermatology and Senior Vice President for Academic Affairs, Henry Ford Health System. Past President, American Academy of Dermatology, Detroit, USA

Nanja van Geel, MD, PhD, Professor, Department of Dermatology, Ghent University Hospital, Ghent, Belgium

Amit G. Pandya, MD, Professor, Department of Dermatology, University of Texas, Southwestern Medical Center, Dallas, USA

Table of Contents
List of Contributors
1 Introduction
2 Melanocyte and melanogenesis: Applied anatomy and physiology
3 Epidemiology of Vitiligo
4 Pathogenesis of vitiligo
5 Understanding the mechanisms of repigmentation in vitiligo
6 Classification and Clinical Features of vitiligo
7 Outcome Measures for Vitiligo
8 Evaluation and treatment of the psychosocial burden of vitiligo
9 Patient support, education and compliance
10 Goals of Vitiligo Treatment, and Evidence Based Practice Guidelines for Medical and Surgical Management
11 The concept of stability of vitiligo and stabilization therapies
12 Narrowband Ultraviolet B Phototherapy in Vitiligo
13 UVA-based Phototherapy: PUVA, PUVA-sol, UVA1 phototherapy
14 Immunomodulators and immunosuppressives in Vitiligo
15 Topical Glucocorticoids, Topical Calcineurin Inhibitors and Topical Vitamin D3 Analogues
16 Targeted Phototherapy in Vitiligo
17 OTHER THERAPIES IN VITILIGO
18 Biologic therapies for vitiligo
19 Evidence toward integrated management of Vitiligo combining Ayurveda and Homeopathy with Modern Dermatology
20 History and chronology of development of surgical therapies for vitiligo
21 Patient selection, pre and postoperative information in surgical therapies for vitiligo
22 Classification of surgical therapies for vitiligo
23 Minigrafting for vitiligo
24 Suction blister epidermal grafting
25 Thin and ultra-thin skin grafts for vitiligo
26 Treatment of leukoderma by transplantation of ultra-thin epidermal sheets
27 Surgical management of leukotrichia
28 Mesh grafting in vitiligo
29 Smash Grafting
30 Therapeutic Needling and Needling Micrografting
31 Complications and limitations of melanocyte transplantation
32 Treatment of leukoderma by transplantation of basal cell layer suspension
33 Non cultured extracted follicle outer root sheath cell suspension transplantation
34 Long term results of non cultured epidermal cellular grafting in vitiligo
35 Simplified Non-Cultured Cellular Grafting
36 Novel methods of preparing epidermal cell suspension for transplantation in vitiligo
37 Setting up a tissue culture laboratory
38 Treatment of leukoderma by transplantation of cultured autologous melanocytes
39 Transplantation of in-vitro cultured epithelial grafts for vitiligo and piebaldism
40 Application of lasers for abrasion in transplantation procedures for vitiligo
41 Cell delivery on recipient skin
42 Safety concerns in transplantation of in vitro cultured cellular grafts
43 Surgical management of lip vitiligo, eyelids and genitals
44 Surgical management of acral vitiligo
45 Surgical management of leukotrichia
46 Surgical treatments of leukodermas other than vitiligo vulgaris
47 Ethnic issues in management and Sun protection
48 Management Issues for Vitiligo in Children and Pregnant Women
49 Combination treatments for Vitiligo
50 Micropigmentation
51 CAMOUFLAGE IN VITILIGO
52 Depigmentation treatment for vitiligo: bleaching cream, laser and cryotherapy
53 Future directions in medical and surgical management of vitiligo
54 Informed consent