Articular Cartilage of the Knee

Harpal K. Gahunia, MSc, PhD, President and CEO, Orthopaedic Science Consulting Services, Oakville, ON, Canada Allan E. Gross, MD, FRCSC, Bernard I. Ghert Family Foundation, Chair, Lower Extremity Reconstructive Surgery, Professor, Department of Surgery, University of Toronto and Mount Sinai Hospital, Toronto, ON, Canada Kenneth P. H. Pritzker, MD, FRCPC, Professor, Department of Laboratory Medicine & Pathobiology and Department of Surgery, University of Toronto, Pathologist, Pathology & Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada Paul S. Babyn, MD, FRCPC, Head, Department of Medical Imaging, University of Saskatchewan and Saskatoon Health Region, Royal University Hospital, Saskatoon, SK, Canada Lucas Murnaghan, MD, Med, FRCSC, Assistant Professor, Department of Surgery, University of Toronto, Orthopedic Surgeon, The Hospital for Sick Children and Women’s College Hospital, Toronto, ON, Canada

Part I: Normal Articular Cartilage.- Structure and Function of Articular Cartilage.- Growth and Development of Articular Cartilage.- Part II: Aging, Degeneration and Physiologic Articular Cartilage Healing.- Articular Cartilage: Homeostasis, Aging and Degeneration.- Articular Cartilage Degradation: Biochemical Markers and Dynamic Loading.- Part III: Knee Articular Cartilage Injury: Evaluation and Assessment.- Acute and Chronic Traumatic Cartilage Injuries of the Knee.- Diagnostic Imaging of Knee Cartilage Injury: Evaluation and Assessment.- Assessment of Knee Cartilage Injury: Arthroscopic Evaluation and Classification.- Part IV: Repair of Knee Articular Cartilage Injury: Non-Operative Approach.- Physical and Rehabilitative Therapy for Knee Cartilage Injury and Disease.- Pharmacologic Agents for Knee Articular Cartilage Injury and Disease.- Part V: Repair of Knee Articular Cartilage: Surgical Approach.- Osteochondritis Dissecans of the Knee: Pathophysiology and Treatment.- Surgical Approach to Articular Cartilage Repair.- Clinical Outcome Assessment of Repaired Articular Cartilage.- Part VI: Qualitative and Quantitative Assessment of Articular Cartilage Repair.- Pre- and Post-Operative Imaging of Knee Articular Cartilage.- MRI of the Ultrastructural Composition of Articular Cartilage in Disease and Repair.- Histopathological Evaluation of Articular Cartilage Disease and Repair.- Part VII: Research in Cartilage Repair and Cartilage Engineering Strategies.- Human Derived Cells in Chondral or Osteochondral Repair.- Relevance of Engineered Scaffolds for Cartilage Repair.- Commercially Available Bio-Engineered Cartilage Grafts.- Part VIII: Future Prospects for Knee Articular Cartilage Therapy.- Knee Articular Cartilage: Future Directions for Research and Practice.