MicroRNA and Cancer
Humana Press Inc. (Verlag)
978-1-4939-5774-3 (ISBN)
•Overview of microRNA biogenesis, computational prediction of new miRNAs in the cancer genome, and miRNA-based therapeutic approaches for cancer treatment
•Detailed experimental protocols in miRNA detection with novel and high-throughput technology, miRNA library cloning, miRNA epigenetic regulation, and miRNA pathway study
•Stepwise computational and bioinformatic procedures for miRNA complex networks in cancer genomes with a variety of softwares and programs
•Cross-cited notes on troubleshooting and avoiding known pitfalls
Authoritative and cutting-edge, MicroRNA and Cancer: Methods and Protocols serves researchers with the basic principles of experimental and computational methods for microRNA study in cancer research and provides a firm grounding for those who wish to further develop their own applications and tailor them to their own specific research needs.
MicroRNA Biogenesis and Cancer.- Computational Identification of MiRNAs Involved in Cancer.- The Principles of MiRNA-Masking Antisense Oligonucleotides Technology.- The Concept of Multiple-Target Anti-miRNA Antisense Oligonucleotide Technology.- Modulation of MicroRNAs for Potential Cancer Therapeutics.- Detection of MicroRNAs in Cultured Cells and Paraffin-Embedded Tissue Specimens by In situ Hybridization.- MicroRNA Northern Blotting, Precursor Cloning, and Ago2-Improved RNA Interference.- MiRNA Profiling on High Throughput OpenArray™ System.- Silicon Nanowire Biosensor for Ultrasensitive and Label-Free Direct Detection of miRNAs.- High Throughput and Reliable Protocols for Animal microRNA Library Cloning.- MicroRNA Regulation of Growth Factor Receptor Signalling in Human Cancer Cells.- Epigenetic Regulation of MicroRNA Expression in Cancer.- In vitro Functional Study of miR-126 in Leukemia.- Prediction of the Biological Effect of Polymorphisms within MicroRNA Binding Sites.- The Guideline of the Design and Validation of MiRNA Mimics.- Analysis of Targets and Functions Co-Regulated by MicroRNAs.- Utilization of SSCprofiler to Predict a New MiRNA Gene.- MicroRNA-Profiling Using Fluorescence-Labeled Beads: Data Acquisition and Processing.
Erscheinungsdatum | 19.08.2017 |
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Reihe/Serie | Methods in Molecular Biology ; 676 |
Zusatzinfo | X, 273 p. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
ISBN-10 | 1-4939-5774-0 / 1493957740 |
ISBN-13 | 978-1-4939-5774-3 / 9781493957743 |
Zustand | Neuware |
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