Genetic Toxicology
Humana Press Inc. (Verlag)
978-1-4939-5736-1 (ISBN)
Intuitive and cutting-edge, Genetic Toxicology: Principles and Methods provides crucial support to both laboratory workers in providing quality information on the appropriate application of techniques and to study directors in their assay selection and protocol design in this vital field.
The Application of Structure Activity Relationships to the Prediction of the Mutagenic Activity of Chemicals.- Bacterial Mutagenicity Assays: Test Methods.- The Mouse Lymphoma Assay.- Mammalian Cell HPRT Gene Mutation Assay: Test Methods.- The In Vitro Mammalian Chromosome Aberration Test.- The Interpretation and Analysis of Cytogenetic Data.- The In Vitro Micronucleus Assay.- The In Vitro and In Vivo Comet Assays.- Assessment of DNA Interstrand Crosslinks (ICLs) Using the Modified Alkaline Comet Assay.- 32P-Postlabelling for the Sensitive Detection of DNA Adducts.- Methods for the Detection of DNA Adducts.- The GADD45a-GFP GreenScreen HC Assay.- Real Time Reverse-Transcription Polymerase Chain Reaction (RT-PCR): Technical Considerations for Gene Expression Analysis.- Cytogenetic In Vivo Assays in Somatic Cells.- Cytogenetic Methods in Human Biomonitoring: Principles and Uses.- The Measurement of Induced Genetic Change in Mammalian Germ Cells.- Transgenic Animal Mutation Models: A Review of the Models and How They Function.- Analysis of Genotoxicity Data in a Regulatory Context.
Erscheinungsdatum | 19.08.2017 |
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Reihe/Serie | Methods in Molecular Biology ; 817 |
Zusatzinfo | 46 Illustrations, color; 68 Illustrations, black and white; XVI, 433 p. 114 illus., 46 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
Medizin / Pharmazie ► Pharmazie | |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
ISBN-10 | 1-4939-5736-8 / 1493957368 |
ISBN-13 | 978-1-4939-5736-1 / 9781493957361 |
Zustand | Neuware |
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