Alzheimer's Disease and Dementia

Benjamin T. Mast, PhD, ABPP, is a board-certified clinical geropsychologist and a fellow with the Gerontological Society of America. He serves as Professor and Vice Chair in the Department of Psychological & Brain Sciences at the University of Louisville. He is the author of several books on dementia and is Co-Editor in Chief of the American Psychological Association Handbook of Clinical Geropsychology (2015). He is the President of the Society of Clinical Geropsychology (American Psychological Association, Division 12, Section 2). Brian P. Yochim, PhD, ABPP, is a board-certified clinical neuropsychologist at the VA Saint Louis Health Care System. His research, clinical work, and teaching has focused on older adults and dementia. He has served as Past-President of the Society of Clinical Geropsychology (American Psychological Association, Division 12, Section 2) and has over 30 publications in neuropsychology and aging.

Preface
1 Description
1.1 Terminology
1.2 Definition
1.2.1 Dementia
1.2.2 Mild Cognitive Impairment
1.3 Epidemiology
1.4 Course and Prognosis
1.4.1 Stage 1 - Normal
1.4.2 Stage 2 - Subjective Memory
Complaints
1.4.3 Stage 3 - Mild Cognitive Impairment
1.4.4 Stage 4 - Mild Dementia
1.4.5 Stage 5 - Moderate Dementia
1.4.6 Stage 6 - Moderately Severe
Dementia
1.4.7 Stage 7 - Severe Dementia
1.5 Differential Diagnosis
1.6 Comorbidities
1.7 Diagnostic Procedures and
Documentation
2 Theories and Models of Alzheimer's
Disease and Dementia
2.1 Alzheimer's Disease
2.1.1 Neuropathology
2.1.2 Cognitive Symptoms
2.2 Lewy Body Disease
2.2.1 Neuropathology
2.2.2 Cognitive Symptoms
2.3 Vascular Disease
2.3.1 Neuropathology
2.3.2 Cognitive Symptoms
2.4 Frontotemporal Dementia
2.4.1 Neuropathology
2.4.2 Cognitive Symptoms
3 Diagnosis and Treatment Indications
3.1 Level 1 - Neurobiological Changes
3.2 Level 2 - Cognitive Functioning
3.3 Level 3 - Behavioral and Psychological
Symptoms of Dementia
3.4 Level 4 - Caregiving and Family Issues
4 Treatment of Alzheimer's Disease and
Dementia
4.1 Methods of Treatment
4.1.1 Dementia Education
4.1.2 Medication Treatment for Cognitive
Symptoms
4.1.3 Cognitive Interventions
4.1.4 Lifestyle Interventions and Prevention
4.1.5 Medication Treatment of BPSD
4.1.6 Psychosocial and Person-Centered
Treatment
4.1.7 Caregiver Interventions
4.1.8 Dyadic Interventions
4.1.9 Future Care Planning and
Decision-Making Capacity
4.2. Mechanisms of Action
4.2.1 Pharmacological
4.2.2 Brain Health and Cognitive Reserve
4.2.3 Reducing Excess Disability
4.2.4 Promoting Caregiver Self-Efficacy and
Caregiving Skills
4.3 Efficacy and Prognosis
4.4 Variations and Combinations of Methods
4.5 Problems in Carrying Out Treatments
4.5.1 Need for Assistance Carrying Out
Treatment
4.5.2 Treatment Availability Based on
Setting
4.5.3 Medication Side Effects
4.6 Multicultural Issues
5 Case Vignette
6 Further Reading
7 References
8 Appendix: Tools and Resources