Brain Arteriovenous Malformations

Vladimír Benes, MD, PhD Prague, Czech Republic Ondrej Bradác, MD, MSc, PhD Prague, Czech Republic

Introduction.- Motivation to this study.- AVM definition and angioarchitecture.- Feeding arteries.- Associated aneurysms.- Nidus component.- Draining veins.- Genetics of arteriovenous malformations.- Epidemiology of AVM.- Physiology of arteriovenous malformations.- Arterial side.- Steal phenomenon.- Normal perfusion pressure breakthrough.- Venous side.- Occlusive hyperemia.- Compartmental model of AVM nidus.- AVM presentation.- Hemorrhagic presentation.- Morbidity and mortality of AVM related intracranial haemorrhage.- Epilepsy presentation.- Focal neurologic deficit (FND).- Natural course.- AVM grading.- Surgical AVM grading.- Radiosurgical AVM grading.- Imaging.- Catheter angiography.- Magnetic resonance imaging.- Computed tomography.- Treatment for brain AVMs.- Literature series.- Surgery.- Endovascular embolization.- Stereotactic radiosurgery.- Combined treatment.- ARUBA study comments.

"With this book, the authors provide a useful vade mecum of one the most challenging cerebrovascular diseases, brain arteriovenous malformation (AVM). ... Intended for a young audience of specialists in the field, the book offers a synthetic picture of the current understanding and management of cerebral AVM for those who are first approaching this complex disease. ... This book, encompassing different fields, provides a comprehensive knowledge base in cerebral AVM, adding a valuable resource to the current literature." (Fady T. Charbel, Doody's Book Reviews, January, 2018)