Precision Molecular Pathology of Lung Cancer

Philip T. Cagle, Timothy Craig Allen, Mary Beth Beasley, Lucian R. Chirieac, Sanja Dacic, Alain C. Borczuk, Keith M. Kerr, Lynette M. Sholl, Bryce Portier, Eric H. Bernicker (Herausgeber)

Buch | Hardcover

VIII, 296 Seiten

2017 | 2nd ed. 2018
Springer International Publishing (Verlag)
978-3-319-62940-7 (ISBN)

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This book offers information and insight into the molecular basis for lung cancer, including precursor and preinvasive lesions, molecular diagnosis, molecular targeted therapy, molecular radiology and related topics for lung cancer and for specific cell types.

This new edition provides the latest information and insights into the molecular basis for lung cancer. Since the publication of the previous edition of this volume, dramatic changes have occurred with the classification of lung cancer, biomarker testing, and molecular therapy. The book covers these changes, providing updates and new insights on the background of lung cancer, testing methods, and the molecular pathology of specific cell types, including adenocarcinoma, squamous cell carcinoma, small cell carcinoma, and precursor and preinvasive lesions.
Authored by experts in the field, Precision Molecular Pathology of Lung Cancer, Second Edition remains one of the few books that comprehensively covers the new molecular pathology of lung cancer and is a valuable resource for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, and thoracic radiologists.

Philip T. Cagle, MD Houston Methodist Hospital Department of Pathology & Genomic Medicine 6565 Fannin St Houston, TX 77030 Timothy C. Allen, MD The University of Texas Medical Branch Department of Pathology 301 University Boulevard Galveston, TX 77555 Mary Beth Beasley, MD

I. Background.- 1. Precision Medicine of Lung Cancer: Introduction.- 2. Lung Cancer Epidemiology and Demographics.- 3. Genetic Susceptibility to Lung Cancer.- 4. Lung Cancer Stem Cells.- 5. The 2015 World Health Organization Classification of Lung Cancer: Overview.- II. Testing Methods.- 6. Preanalytic considerations.- 7. Mutation testing of lung cancer biomarkers.- 8. Translocation testing of lung cancer biomarkers.- 9. Immunohistochemistry of lung cancer biomarkers.- 10. Next Generation and Third Generation Sequencing of lung cancer biomarkers.- III. Molecular Pathology of Specific Cell Types.- 11. Mutations as Predictive Biomarkers for Adenocarcinoma.- 12. Translocations as predictive Biomarkers for Adenocarcinoma.- 13. Predictive Biomarkers for Squamous Cell Carcinoma.- 14. Molecular Pathology of Small Cell Carcinoma.- 15. Molecular Pathology of Uncommon Carcinomas.- 16. Molecular Pathology of Lung Cancer Metastases.- 17. Molecular Pathology of Precursor and Preinvasive Lesions.- IV. General and Emerging Fields in Molecular Pathology of Lung Cancer.- 18. Prognostic biomarkers in lung cancer.- 19. Biomarkers and Differing Therapy Modalities.- 20. Immuno-oncology of Lung Cancer.- 21. Liquid Biopsy.

Erscheinungsdatum	03.12.2017
Reihe/Serie	Molecular Pathology Library
Zusatzinfo	VIII, 296 p. 57 illus., 55 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	549 g
Themenwelt	Medizinische Fachgebiete ► Chirurgie ► Herz- / Thorax- / Gefäßchirurgie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
Schlagworte	Adenocarcinoma • cardiothoracic surgery • Lungenkrebs • Medicine • Medicine: general issues • Oncology • Pathology • Precursor lesions • preinvasive lesions • squamous cell carcinoma • targeted therapy • Thoracic Surgery
ISBN-10	3-319-62940-9 / 3319629409
ISBN-13	978-3-319-62940-7 / 9783319629407
Zustand	Neuware