Drug Induced Liver Disease
Churchill Livingstone (Verlag)
978-0-443-04368-0 (ISBN)
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Liver disease induced by drugs poses many challenging problems to all who have to deal with them. This book should help the reader to understand, diagnose, treat and ultimately prevent, hepatic drug reactions. The book brings together all that is currently known about drug-induced liver disease in a format which is explanatory as well as comprehensive. It covers all aspects, including the way in which the liver deals with foreign compounds, biochemical cell defence mechanisms and physiological functions of the liver. It should help the reader to identify the drug incriminated in drug-induced hepatobiliary disorders as well as providing a guide to differentiation between drug-induced hepatobiliary disorders and those which are not drug-induced.
SECTION 1 UNDERLYING CONCEPTS: Role of the Liver in Drug Metabolism. Biochemical Mechanisms. The Immunological Mediation of Drug Reactions Affecting the Liver SECTION2 GENERAL ASPECTS of DRUG-INDUCED LIVER DISEASE: Importance of Drug-Induced Liver Disease. The Clinicopathological Spectrum of Drug-Induced Liver Diseases. Histopathology of Drug-Induced Liver Disease. Diagnosis of Drug-Induced Liver Disease. Management of Drug-Induced Liver Disease SECTION 3 CAUSATIVE AGENTS and SPECIFIC FORMS of DRUG-INDUCED LIVER DISEASE, Compendium of Agents Reported to Cause Drug-Induced Liver Disease. Paracetamol-Induced Hepatotoxicity. Cytotoxic Lesions : Acute Fatty Change and Zonal Necrosis. Drug-Induced Acute Hepatitis. Drug-Induced Granulomatous Hepatitis. Drug-Induced Cholestasis. Liver Disease Produced By Nonsteroidal Anti-Inflammatory Drugs. Liver Disease Due to Anaesthetic Agents. Drug-Induced Chronic Active Hepatitis. Drug-Induced Steatohepatitis. Drug-Induced Hepatic Fibrosis, Cirrhosis. Drug-Induced Vascular Disorders. Liver Disease Caused By Anti-Cancer Drugs. Hepatic Tumours. Liver Disease Due to Environmental Toxins References. Index
Vorwort | Willis C. Maddrey |
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Zusatzinfo | 148 illus |
Verlagsort | London |
Sprache | englisch |
Maße | 302 x 45 mm |
Gewicht | 1670 g |
Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Hepatologie |
ISBN-10 | 0-443-04368-X / 044304368X |
ISBN-13 | 978-0-443-04368-0 / 9780443043680 |
Zustand | Neuware |
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