Isolation and Molecular Characterization of Circulating Tumor Cells (eBook)

 Preface. 1Circulating Tumor Cells as Cancer Biomarkers.-2Strategies for Isolation and Molecular Profiling of Circulating Tumor Cells3Aptamer-Based Methods for Detection of Circulating Tumor Cells and Their Potential for Personalized Diagnostics4Development of a Protocol for Single-Cell Analysis of Circulating Tumor Cells in Patients with Solid Tumors5Flow Cytometric Methods for Circulating Tumor Cell Isolation and Molecular Analysis6Enrichment and Detection of Circulating Tumor Cells and Other Rare Cell Populations by Microfluidic Filtration7Detection and Enumeration of Circulating Tumor Cells with Invasive Phenotype8Molecular Profiling and Significance of Circulating Tumor Cell Based Genetic Signatures9Detection of Gene-Rearrangements in Circulating Tumor Cells: Examples of ALK-, ROS1-, RET-Rearrangements in Non-Small-Cell Lung Cancer and ERG-Rearrangements in Prostate Cancer10Enrichment, Isolation, and Molecular Characterization of EpCAM-Negative Circulating Tumor Cells11Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells12Mesenchymal-Epithelial Transition in Circulating Tumor Cells of Small Cell Lung Cancer13Clinical Relevance of a Candidate Stem Cell Marker, p75 Neurotrophin Receptor (p75NTR) Expression in Circulating Tumor Cells14Personalized Treatment Through Detection and Monitoring of Genetic Aberrations in Single Circulating Tumor Cells15Glycan Markers as Potential Immunological Targets of Circulating Tumor Cells 16Significance of EGFR Expression in Circulating Tumor Cells