Cardiovascular OCT Imaging

Ik-Kyung Jang, MD, PhD is Professor of Medicine at Harvard Medical School, Director of the Cardiology Laboratory for Integrative Physiology and Imaging (CLIPI) at Massachusetts General Hospital. Dr. Jang came to Massachusetts General Hospital in 1987 from Leuven University in Belgium, where he has completed his residency in medicine and fellowship in cardiology. He also successfully defended his doctorate thesis at the same university under the supervision of Professor Desire Collen. After his advanced fellowship in cardiology at MGH, he joined the staff and is currently working as a Physician and an interventional cardiologist in the Cardiology Division. His research interest has been acute coronary syndromes including acute myocardial infarction. His earlier research focused on pharmacology and physiology of thrombosis and thrombolysis including thrombin hypothesis and platelet inhibition. For the last fifteen years he has pioneered the application of intravascular Optical Coherence Tomography (OCT) to patients to better characterize coronary plaques and to understand the mechanisms of plaque rupture. In 2010 Dr. Jang established an international OCT Registry, which has more than 2000 patients from 20 sites across 6 countries.

History of OCT.- Physics of OCT.- Histology validation of OCT images.- Characterization of coronary plaques.- Basic interpretation skill.- Early stent evaluation.- Late stent changes.- Bioabsorbable stent.- Stent thrombosis.- Neoatherosclerosis.- Consensus document.- Future development.  

"This text is a guide to cardiovascular use of optical coherence tomography (OCT). ... The book contains 15 chapters with a useful index, occupying 222 pages and including numerous representative illustrations. ... Although this volume is mainly addressed to interventional cardiologists, providing background and useful hints, we recommend this fascinating book to all clinicians interested in vascular biology to improve their understanding of the role and evolution of high-risk plaque in the pathogenesis of acute coronary syndrome." (Valeria Gaudieri and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 43, 2016)

"This book provides an all-encompassing overview of cardiovascular OCT imaging - from a historical perspective to projections about future uses of this exciting technology. ... The intended audience is interventional cardiologists and cardiovascular researchers. ... This book does a great job of covering both the basic and the complex facets of OCT. The text is concise and well focused." (Evan S. Jacobs, Doody's Book Reviews, May, 2015)