Stroke Genetics -

Stroke Genetics

Buch | Hardcover
XII, 431 Seiten
2017 | 2nd ed. 2017
Springer International Publishing (Verlag)
978-3-319-56208-7 (ISBN)
181,89 inkl. MwSt
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This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.

Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.

Pankaj Sharma, MD, PhD, FRCPReader & Consultant NeurologistImperial College London & Hammersmith HospitalsLondon, UKJames F. Meschia, MDChair, Department of NeurologyMayo ClinicJacksonville, Florida, USA

Introduction.- Familial stroke epidemiology.- Association study results.- GWAS.- Aneurysms/carvernous/AVM.- ICH/amyloid/microbleeds.- CADASIL.- Fabry.- MELAS.- Sickle.- Other monogenic.- White matter disease.- Carotid atherosclerosis.- Dissection.- Pharmacogenomics.- Non-Caucasian stroke genetics.- Small vessel disease.- Genetics of neuroimaging in stroke.- Cerebrovenous thrombosis.- Ethics.

Erscheinungsdatum
Zusatzinfo XII, 431 p. 39 illus., 26 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Gewicht 882 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Studium 2. Studienabschnitt (Klinik) Humangenetik
Schlagworte CADASIL • Cerebral hemorrhage • Clinical & internal medicine • Clinical & internal medicine • Fabry • Genetics • Genome • GWAS • Human genetics • Hypertension • Internal Medicine • medical genetics • Medicine • Medicine: general issues • MELAS • Neurology • Neurology & clinical neurophysiology • Neurology & clinical neurophysiology • Schlaganfall • Stem Cell • stroke
ISBN-10 3-319-56208-8 / 3319562088
ISBN-13 978-3-319-56208-7 / 9783319562087
Zustand Neuware
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