Essential Neonatal Medicine

Sunil Sinha Professor of Paediatrics University of Durham Consultant Neonatologist James Cook University Hospital Middlesbrough, UK Lawrence Miall Consultant Neonatologist Quality Lead, Leeds Children’s Hospital Leeds General Infirmary Leeds Teaching Hospitals NHS Trust Leeds, UK Luke Jardine Deputy Director Neonatology, Mater Mothers’ Hospital Senior Staff Specialist Neonatology, Mater Mothers’ Hospital Honorary Researcher, Mater Research Associate Professor, The University of Queensland Australia

Preface to the Sixth Edition vii

Acknowledgements vii

Preface to the First Edition viii

Abbreviations ix

How to use your textbook xi

About the companion website xii

1 The fetus, placenta and changes at birth 1

2 Perinatal epidemiology and audit 14

3 Multiple births 19

4 Neonatal consequences of maternal conditions 25

5 Resuscitation at birth 33

6 Examination of the newborn 46

7 Birth injury 65

8 Genetic disorders 73

9 Infant feeding and nutrition 82

10 Infection in the newborn 98

11 The extreme preterm infant 114

12 The low-birthweight infant 124

13 Respiratory physiology and respiratory support 131

14 Respiratory disorders 144

15 Apnoea, bradycardia and upper airway obstruction 160

16 Cardiovascular disorders 168

17 Gastrointestinal and abdominal disorders 186

18 Renal disorders 201

19 Jaundice 210

20 Haematological disorders 221

21 Endocrine and metabolic disorders 233

22 The central nervous system 250

23 Neurodevelopmental follow-up and assessment of hearing and vision 270

24 Developmental care and the neonatal environment 277

25 Organization of perinatal services 287

26 Neonatal transport 291

27 Discharge and follow-up of high-risk infants 297

28 Parent–infant attachment and support for parents of critically ill infants 306

29 Ethical issues and decision-making process in the treatment of critically ill newborn infants 311

30 End-of-life care and palliative care 316

Index 323