Selenium -

Selenium

Present Status and Perspectives in Biology and Medicine

Gerhard N. Schrauzer (Herausgeber)

Buch | Softcover
316 Seiten
1988 | Softcover reprint of the original 1st ed. 1988
Humana Press Inc. (Verlag)
978-0-89603-154-8 (ISBN)
106,99 inkl. MwSt
This volume reflects clinical and experimental research on selenium. Papers focus on biomedical and ecological aspects of this element, with special emphasis on the distribution of selenium in body organs and fluids, and its role and mechanisms in human disease.
The papers and reviews in the present volume are in part regular contributions submitted for publication in Biological Trace Element Research, and in part invited papers from participants of the International Symposium "Present Status and Perspectives of Sele- nium in Biology and Medicine," held on May 2 and 3, 1987, at the Eu- ropean Academy, Nonnweiler /Trier, FRG. The Symposium focused on ecological and biomedical aspects of selenium with emphasis on the manifestations of selenium deficiency in different countries, the distribution of selenium in human organs and body fliuds, the roles of selenium in health and disease, its anti carcinogenic action, effects of supplementation, and therapeutic applications. Organized jointly by the International Association of Bioinor- ganic Scientists and BioSynopsia, a Nonprofit Subsidiary of the Tech- nology Center, Stuttgart, the scientific board consisted of Professors W. Hartfiel, Bonn, FRG, G. N. Schrauzer, La Jolla, CA, USA, and H. Zumkley, Muenster, FRG.

Selenium Deficiency in the Federal Republic of Germany.- Selenium: Geochemical Distribution and Association with Human Heart and Cancer Death Rates and Longevity in China and the United States.- The Organ Distribution of Selenium in German Adults.- Correlations of Blood Selenium with Hematological Parameters in West German Adults.- Selenium in Platelets.- Effect of Selenium Supplementation on Platelet Selenium, Glutathione Peroxidase, and Aggregation.- Selenite Metabolism in Rat and Human Blood.- Selenium, Cadmium, Lead, and Mercury Concentrations in Human Breast Milk, in Placenta, Maternal Blood, and the Blood of the Newborn.- Comparison of Whole Blood Selenium Values and Erythrocyte Glutathione Peroxidase Activities of Normal Individuals on Supplementation with Selenate, Selenite, L-Selenomethionine, and High Selenium Yeast.- Clinical Aspects of Selenium Metabolism.- Selenium in Total Parenteral Nutrition.- Selenium in Cardiology and Angiology.- Abnormalities of Blood Selenium and Glutathione Peroxidase Activity in Patients with Acquired Immunodeficiency Syndrome and Aids-Related Complex.- Selenium in Chronic Neurologic Diseases: Multiple Sclerosis and Batten’s Disease.- The Distribution of Selenium in Human Blood Samples of Israeli Population—Comparison between Normal and Breast Cancer Patients.- Arsenic, Selenium, and Zinc in Patients with Blackfoot Disease.- Selenium: Preclinical Studies of Anticancer Therapeutic Potential.- Selenium Chemoprevention of Liver Cancer in Animals and Possible Human Applications.- Biochemical and Cellular Aspects of the Anticancer Activity of Selenium.- Antagonistic Effect of Selenite on Tumor Promoter Induced Cell Proliferation in Cultures of Rat Tongue Epithelium.- Zinc-Selenium Interaction in the Rat.- Selenium in the AnteriorPituitary of the Rat after a Single Injection of 75Se Sodium Selenite.- Experimental Study on Interactions between Selenium and Tin in Mice.- Author Index.

Zusatzinfo 7 Illustrations, black and white; 316 p. 7 illus.
Verlagsort Totowa, NJ
Sprache englisch
Maße 178 x 254 mm
Themenwelt Medizin / Pharmazie Studium 1. Studienabschnitt (Vorklinik)
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Humanbiologie
ISBN-10 0-89603-154-3 / 0896031543
ISBN-13 978-0-89603-154-8 / 9780896031548
Zustand Neuware
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