Human T-Lymphotropic Viruses

Serological and Molecular Methods to Study Epidemiological Aspects of Human T-Cell Lymphotropic Virus Type 1 Infection.- Molecular Epidemiology Database for Sequence Management and Data Mining.- Reporter Systems to Study HTLV-1 Transmission.- Quantitative Analysis of Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection Using Co-Culture with Jurkat LTR-Luciferase or Jurkat LTR-GFP Reporter Cells.- Isolation of Exosomes from HTLV-Infected Cells.- A Luciferase Functional Quantitative Assay for Measuring NF-ĸB Promoter Transactivation Mediated by HTLV-1 and HTLV-2 Tax Proteins.- Generation of a Tet-On Expression System to Study Transactivation Ability of Tax-2.- EGF Uptake and Degradation Assay to Determine the Effect of HTLV Regulatory Proteins on the ESCRT-Dependent MVB Pathway.- Methods for Identifying and Examining HTLV-1 HBZ Post-Translational Modifications.- High-Throughput Mapping and Clonal Quantification of Retroviral Integration Sites.- STR Profiling of HTLV-1-Infected Cell Lines.- Expression of HTLV-1 Genes in T-cells Using RNA Electroporation.- Quantification of Cell Turnover in the Bovine Leukemia Virus Model.- Analysis of NK Cell Function and Receptor Expression During HTLV-1 and HTLV-2 Infection.- Overview of Targeted Therapies for Adult T-Cell Leukemia/Lymphoma.