Human Pathogenic Papillomaviruses

Harald ZurHausen (Herausgeber)

XIII, 274 Seiten
1994
Springer Berlin (Hersteller)
978-3-540-57193-3 (ISBN)

Lese- und Medienproben

98,17 inkl. MwSt
  • Titel ist leider vergriffen;
    keine Neuauflage
  • Artikel merken
An examination of the role of specific human papillomavirus (HPV) types in various malignant tumours, which summarizes aspects of HPV research and its relationship to human cancers.
The etiologic involvement of specific human papillomavirus (HPV) types in cancer of the cervix and their role in a substantial proportion of other anogenital cancers and cancers of the oropharynx (most prominently cancers of the tonsils and of the larynx) label HPV as a prime target for the analysis of mechanisms leading to the development of malignant tumours in humans. As in other viral infections linked to human cancers, HPV infection is not sufficient for the induction of malignant growth. It emerges, however, as the main factor, introducing new genes into the latently infected cells whose function as oncogenes have become clearly established during the past few years. The regulation of their expression by specific host cell proteins, stimulated by intra- and intercellular signals, seems to represent a primary defence mechanism against the induction of unrestricted growth. The failure of this host cell control system, on the other hand, by mutational changes affecting the host cell genome, appears to predispose for malignant conversion.
This volume summarizes various aspects of HPV research and its relationship to human cancers and provides an overview of current topics in an exciting research field.
Reihe/Serie Current Topics in Microbiology and Immunology ; Vol.186
Zusatzinfo 37 figs., 15 tabs.
Verlagsort Berlin
Sprache englisch
Gewicht 596 g
Einbandart gebunden
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Schlagworte Papillomviren (HPV)
ISBN-10 3-540-57193-0 / 3540571930
ISBN-13 978-3-540-57193-3 / 9783540571933
Zustand Neuware
Haben Sie eine Frage zum Produkt?