Non-Hodgkin's Lymphomas

Part 1 Lymphomagenesis: Lymphocyte differentiation; Adult T-cell leukaemia/Lymphoma - a model of retrovirus-induced lymphomagenesis; Burkitt's lymphoma and Epstein-Barr virus-associated lymphoid malignancies - models for lymphomagenesis; T(14;18) translocation. Part 2 Methods: Histological and immunohistochemical methods; Genotype. Part 3 Nodal Non-Hodgkin's Lymphomas: The normal lymph node - structure and function; Histological classification; Staging of NHLs; Analytical study of the different subtypes of NHLs - clinical, histological and immunohistochemical aspects; NHLs in childhood; NHLs associated with HIV infection. Part 4 Extra-Nodal Non-Hodgkin's lymphomas: Malignant lymphomas of mucosa-associated lymphoid tissues; Primary gastrointestinal NHLs; Pathology of gastro-intestinal NHLs; Cutaneous lymphomas; NHLs of the Mediastinum; NHLs of the lung; Bone marrow involvement; Blood involvement in chronic (mature) B & T lymphoproliferative syndromes; Liver involvement; Spleen involvement; Extra-cranial head-and-neck NHLs; Central nervous system involvement; NHLs of bone; Urogenital localizations. Part 5 Treatment of Non-Hodgkin's Lymphomas: Methodology and problems in the comparison of results; Treatment of lowgrade NHLs; The role of radiation therapy; Treatment of aggressive lymphomas (intermediate and highgrade); Intensive chemoradiotherapy and bone-marrow transplantation; Salvage therapy after failure; Treatment of NHLs in childhood.