Breast Cancer Biology for the Radiation Oncologist -

Breast Cancer Biology for the Radiation Oncologist

Buch | Softcover
VII, 90 Seiten
2016 | 1. Softcover reprint of the original 1st ed. 2015
Springer Berlin (Verlag)
978-3-662-52074-1 (ISBN)
74,89 inkl. MwSt
The first text to elucidate the biological complexities of breast cancer in a way that is relevant to the radiation oncologist covers numerous emerging issues and offers practical therapeutic recommendations based on available clinical evidence.

This is the first textbook of its kind devoted to describing the biological complexities of breast cancer in a way that is relevant to the radiation oncologist. Radiation Oncology has long treated breast cancer as a single biological entity, with all treatment decisions being based on clinical and pathologic risk factors. We are now beginning to understand that biological subtypes of breast cancer may have different risks of recurrence as well as different intrinsic sensitivity to radiotherapy. Multi-gene arrays that have for years been used to predict the risk of distant recurrence and the value of systemic chemotherapy may also have utility in predicting the risk of local recurrence. Additionally, the targeted agents used to treat breast cancer may interact with radiotherapy in ways that can be beneficial or undesirable. All of these emerging issues are extensively discussed in this book, and practical evidence-based treatment recommendations are presented whenever possible.

Biological subtypes of breast cancer.- Oncogene amplification and Herceptin.- Current clinical use of genetic profiling.- Biology of DCIS and progression to invasive disease.- Cancer Stem Cells and Radiotherapy.- Genetic basis of normal tissue radiosensitivity and late toxicity.- Genetic syndromes and radiotherapy in breast cancer.- Experimental therapies in breast cancer.

Erscheinungsdatum
Reihe/Serie Medical Radiology
Radiation Oncology
Zusatzinfo VII, 90 p. 15 illus., 5 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 210 x 279 mm
Gewicht 261 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Medizinische Fachgebiete Radiologie / Bildgebende Verfahren
Schlagworte Biological subtypes of breast cancer • Biology of DCIS • Cancer Stem Cells and Radiotherapy • Experimental therapies in breast cancer • Herceptin • Medicine • Medicine: general issues • Oncogene amplification • Oncology • Radiaton Oncology • radiotherapy
ISBN-10 3-662-52074-5 / 3662520745
ISBN-13 978-3-662-52074-1 / 9783662520741
Zustand Neuware
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