Sexual Precocity

Assesses worldwide experience in treating precocious puberty, and features research on the aetiology of different forms. The text includes clinical treatment data, describes effective therapies for McCune-Allbright syndrome and familial male precocious puberty, and comments on ethical issues.

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In this volume, international experts assess the worldwide experience in treating precocious puberty and highlight major advances in research on the etiology of different forms of precocious puberty. The book features extensive reviews of the clinical data on treatment of gonadotropin-dependent precocious puberty with agonists of gonadotropin-releasing hormone. Other contributors describe effective therapies for two forms of precocious puberty that result from gonadotropin-independent mechanisms: McCune-Albright syndrome and familial male precocious puberty. Several investigators present new basic science research on the etiology of familial male precocious puberty, the molecular basis of the McCune-Albright syndrome, and the intragonadal signalling pathways that play a role in gonadotropin-independent forms of precocious puberty. The book also includes a commentary on psychosocial and ethical issues in the treatment of sexual precocity.