Thyroid Diseases in Childhood

Gianni Bona, is Full Professor in Pediatrics and Chairman of the Division of Pediatrics at University of Western Piedmont, Novara, Italy. He is also Chairman of the Department of Mother and Child's Health, Maggiore della Carità University Hospital, Novara. He is currently Vice-President of The Italian Society of Preventive and Social Pediatrics and has previously served as Vice-President of The Italian Society of Pediatrics (2006-2009) and as President of Italian Society of Pediatric Endocrinology and Diabetology (ISPED) (2003-2005). Dr. Bona is President of the Interuniversity Research Centre of Genomics in Pediatric Endocrinology, Chief Editor of the journal Minerva Pediatrica, and an Editorial Advisory Council Member of Journal of Endocrinological Investigation. He has published more than 460 papers on a range of fields, including pediatric endocrinology and genetics. Filippo de Luca, is Professor of Pediatrics and Director of the Materno-Fetal Department at the University of Messina, Italy, specialized in pediatrics, with wide expertise in endocrinology and diabetes. He is referee in Acta Pediatrica, European Journal of Endocrinology, Journal of Pediatric Endocrinology and Metabolism, Journal of Endocrinological Investigation. He served as President of the Italian Society of Pediatric Endocrinology and Diabetology (ISPED). Alice Monzani, is resident in Pediatrics and PhD student in the Department of Health Sciences, Università del Piemonte Orientale, Novara, Italy. Her recent publications have included original and review articles on natural history and treatment of subclinical hypothyroidism in children, the association of metabolic syndrome and parental obesity, and a novel familial variation of the thyroid hormone receptor beta gene (I276N) associated with resistance to thyroid hormone. She is referee in for Thyroid, Endocrine, Minerva Pediatrica, Seizure.

Thyroid embryogenesis.- Thyroid hormones in fetal development.- Etiology of congenital hypothyroidism.- Neonatal screening for congenital hypothyroidism: what it has taught us about thyroid and brain.- Laboratory aspects in neonatal screening of congenital hypothyroidism.- Epidemiology of congenital hypothyroidism.- Congenital hypothyroidism due to PAX8 mutations.- Transient neonatal hypothyroidism.- Central Hypothyroidism.- Syndromes of resistance to thyroid hormone action.- Management of congenital hypothyroidism.- Neurodevelopmental outcomes in children with congenital hypothyroidism.- Iodine deficiency from pregnancy to childhood.- Thyroid enlargement from newborn to adolescent.- Thyroid nodules and carcinoma.- Autoimmune thyroiditis.- Subclinical hypothyroidism.- Hyperthyroidism.- Generation of functional thyroid from embryonic stem cells.

"In 19 chapters Italian experts, with one Japanese exception, review pediatric thyroid diseases. ... Each chapter is followed by an update reference list. A didactic text, recommended." (Pediatric Endocrinology Reviews (PER), Vol. 13 (3), March, 2016)