Attempts to Understand Metastasis Formation

Buch | Hardcover
304 Seiten
1996
Springer-Verlag Berlin and Heidelberg GmbH & Co. K
978-3-540-60681-9 (ISBN)

Lese- und Medienproben

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In its review of metastasis-related molecules, this second volume of three outlines the regulation of tumour progression and angiogenesis by cytokines, growth factors and motility factors.
Since the mid-1980s the molecular biology of tumour models has revealed the identification of several metastasis-related molecules. This work, in three parts, attempts to review approaches of their mechanisms, regulation and ways to treat their malignant alterations. In this second part the regulation of tumour progression and angiogenesis by cytokines, growth factors and motility factors is outlined.

List of Contents.- Regulation of Tumor Angiogenesis by Organ-Specific Cytokines.- Cytokine-Mediated Tumor-Endothelial Cell Interaction in Metastasis.- Angiogenesis-Regulating Cytokines: Activities and Interactions.- Adhesion Molecules and Tumor Cell-Vasculature Interactions: Modulation by Bioactive Lipid Molecules.- Brain Metastasis: Role of Trophic, Autocrine, and Paracrine Factors in Tumor Invasion and Colonization of the Central Nervous System.- Epithelial Differentiation and the Control of Metastasis in Carcinomas.- Regulation of Autocrine Motility Factor Receptor Expression in Tumor Cell Locomotion and Metastasis.- Metastasis-Related mts 1 Gene.- Alterations in Cell Cycle Control During Tumor Progression; Effects on Apoptosis and the Response to Therapeutic Agents.- Differential Gene Expression in Tumor Metastasis: Nm23.- NM23/Nucleoside Diphosphate Kinase as a Transcriptional Activator of c-myc.- Role of Tiam 1 in Rac-Mediated Signal Transduction Pathways.- Influence of c-myc on the Progession of Human Breast Cancer.

Erscheint lt. Verlag 3.5.1996
Reihe/Serie Current Topics in Microbiology and Immunology ; 213/2
Zusatzinfo 7 black & white tables, biography
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 595 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
ISBN-10 3-540-60681-5 / 3540606815
ISBN-13 978-3-540-60681-9 / 9783540606819
Zustand Neuware
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