The Endometrial Factor

Carlos Simón M.D., PhD is Professor of Obstetrics and Gynecology at the University of Valencia, Spain; Adjunct Clinical Professor, Department of Ob/Gyn, Stanford University School of Medicine, CA, USA; Scientific Director of Instituto Valenciano de Infertilidad (IVI) and IGENOMIX. Linda C Giudice MD, PhD, MSc is Distinguished Professor and Chair, The Robert B. Jaffe, MD Endowed Professor in the Reproductive Sciences, University of California at San Francisco, CA, USA.

Preface. Foreword: An eye to the future. Highlights on the dynamism and multifunctionality of human endometrium in the era of precision medicine. Diagnosis of the Endometrial Factor: New imaging diagnostics. Molecular diagnosis of endometrial receptivity. Molecular diagnosis of endometriosis. Microbiological diagnosis: The human endometrial microbiome-endometritis. Hysteroscopy: An invasive diagnosis. Personalization of the Endometrial Factor: The endometrium in Polycystic Ovary Syndrome. Obesity and the endometrium. Uterine fibroids and the endometrium. New knowledge about adenomyosis. Therapeutic Options of the Endometrial Factor: Hormonal regulation of the endometrium and the effects of hormonal therapies. Abnormal Uterine Bleeding (previously Dysfunctional Uterine Bleeding): How to manage. Inflammation of the endometrium in reproduction. Empirical treatments to improve receptivity: Why not?. Endometrial scratching. Stem Cell Therapies for Atrophic Endometrium and Asherman´s Syndrome. Gestational surrogacy. Uterine transplantation. The Ultimate Goal: Embryo/fetal-maternal cross-talk. Embryo transfer: Fresh, deferred, personalized? Reproductive and obstetrical outcomes.