New Concepts in Asthma

Allergy and immune defence; animal modes of asthma; the rat as experimental model of airway hyper-responsiveness; allergen-induced airway changes in conscious guinea pigs; pharmocologic modulation of antigen; induced airway easinophilia; experimental lung hyperactivity; properties of human lung mast cells; antigenic and peptidergic pathways of most cell activation; release of granule proteins by eosinophils from allergic patients on immunoglobulin-dependent activation; priming eosinophil granulocyte in asthma; prostanoid and leukotrine biosynthesis in peritoneal and airway macrophages of various animal species and man; the role of T-lymphocytes in asthma; T-lymphocyte-eosinophil interactions in allergic inflammation; interleukin-5 and eosinophilia; the interaction of interleukin-1 with actors of asthma; endothelial cells and asthma; intercellular adhesion molecules in pathogenesis of airway hyper-responsiveness; synegism between PAF-acether and IL-S relevance for eosinophil attraction and activation; contribution of histopathology to understanding of asthma; immunopathology of chronic bronchial inflammation.