Molecular Basis of Inherited Disease

Advances in the understanding of human genetic disease have been rapid in recent years. This new edition summarizes for the scientist and clinician the advances in the technology that has made such progress possible.

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Progress in the molecular analysis of human genetic disease has been very rapid over the last three years since the first edition of this book was published. Most of the genes involved in the more common monogenic disorders have been identified and many of the rarer disorders have now been mapped to chromosomal regions. The techniques available for gene mapping have changed substantially, thus facilitating isolation of disease genes from their chromosomal positions. Animal models are being created to allow the detailed study of disease progress. This new edition covers these new developments and should be a valuable reference for students in the biological sciences and clinicians.