Coronary Heart Disease Epidemiology

Coronary heart disease - rise and fall of a modern epidemic; contribution of epidemiology to understanding coronary heart disease; establishing major coronary risk factors; the Framingham experience; the maternal and infant origins of cardiovascular disease; coronary risk factors in childhood; blood pressure in the elderly; coronary heart disease in the elderly; regional variations in heart disease in Great Britain - risk factors and changes in environment; methods in nutritional epidemiology; nutrition and international patterns of disease; design ad analysis of multicentre studies - the INTERSALT study; linoleic acid, antioxidant, vitamins, and coronary heart disease; diabetis, insulin, ethnicity and coronary heart disease; obesity and body fat distribution as predictors of coronary heart disease; exercise versus heart attack - history of a hypothesis; the psycho-social environment, stress, and coronary heart disease; sex difference, hormones and coronary heart disease; atheroma and thrombosis in cardiovascular disease - separate or complementary?; coronary risk factors and non-cardiovascular disease; strategies of prevention - the individual and the population; intervention in high risk groups - blood pressure; reduction of cholesterol-mediated risk - the role of the doctor; cholesterol and coronary heart disease - to screen or not to screen; assessing the evidence - risks and benefits, the role of meta-analysis; secondary prevention of coronary heart disease - drug intervention and life-style modification; the primary prevention of hypertension and the population blood pressure problem; from observation to policy - cholesterol, smoking; monitoring coronary heart disease in the community - why and how?; changing individual behaviour; community programmes in coronary heart disease prevention and health promotion - changing community behaviour; role of organizing public health in cardiovascular disease prevention; national strategies for dietary change.