Cancer Cell Signaling -

Cancer Cell Signaling

Methods and Protocols

Martha Robles-Flores (Herausgeber)

Buch | Softcover
263 Seiten
2016 | Softcover reprint of the original 2nd ed. 2014
Humana Press Inc. (Verlag)
978-1-4939-4648-8 (ISBN)
112,34 inkl. MwSt
Cancer Cell Signaling: Methods and Protocols, Second Edition brings together the most recent advances in cancer cell signaling knowledge along with recent progress in the development of novel strategies and experimental cell models to study human cancer. Opening with a section on targeting cancer cell metabolism as an anticancer strategy, this detailed volume continues with parts describing protocols to study epigenetic control of cancer, protocols to study cancer metastasis, as well as two new techniques for cancer study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions for their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.

Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Second Edition is an ideal guide to the techniques that will aid researchers in exploiting our current knowledge in order to make a profound impact in cancer prevention and treatment.

Use of Biguanides to Improve Response to Chemotherapy.- Evaluating Response to Metformin/Cisplatin Combination in Cancer Cells Via Metabolic Measurement and Clonogenic Survival.- Quantifying the Autophagy-Triggering Effects of Drugs in Cell Spheroids with Live Fluorescence Microscopy.- Interdependency Between Genetic and Epigenetic Regulatory Defects in Cancer.- Experimental Strategies to Manipulate the Cellular Levels of the Multifunctional Factor CTCF.- Use of Serum-Circulating miRNA Profiling for the Identification of Breast Cancer Biomarkers.- Prostate Cancer Detection Using a Non-Invasive Method for Quantifying mi RNAs.- DNA Methylation Analysis of Steroid Hormone Receptor Genes.- Control of Oncogenic mi RNA Function by Light-Activated mi RNA Antagomirs.- Methods for the Study of Long Non-Coding RNA in Cancer Cell Signaling.- Microvesicles as Mediators of Intercellular Communication in Cancer.- In Vivo Rat Model to Study Horizontal Tumor Progression.- An In Vivo Model to Study the Effects of Tumoral Soluble Factors on the Vascular Permeability in Mice.- Use of the Tumor Repressor DEDD as a Prognostic Marker of Cancer Metastasis.- Zebrafish-Based Systems Pharmacology of Cancer Metastasis.- A Flow Cytometry-Based Assay for the Evaluation of Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) in Cancer Cells.- Gene Disruption Using Zinc Finger Nuclease Technology.

Erscheinungsdatum
Reihe/Serie Methods in Molecular Biology ; 1165
Zusatzinfo 27 Illustrations, color; 15 Illustrations, black and white; XI, 263 p. 42 illus., 27 illus. in color.
Verlagsort Totowa, NJ
Sprache englisch
Maße 178 x 254 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Studium
Schlagworte Cancer cell metabolism • Cancer cells • Cancer Metastasis • Cancer prevention and treatment • epigenetics • intercellular communication
ISBN-10 1-4939-4648-X / 149394648X
ISBN-13 978-1-4939-4648-8 / 9781493946488
Zustand Neuware
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