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Acute Lung Injury and Repair

Scientific Fundamentals and Methods

Lynn M. Schnapp, Carol Feghali-Bostwick (Herausgeber)

Buch | Hardcover

VIII, 185 Seiten

2016 | 1st ed. 2017
Springer International Publishing (Verlag)
978-3-319-46525-8 (ISBN)

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lt;p>Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies.

Lynn M. Schnapp, MD Pulmonary, Critical Care, Allergy and Sleep Medicine Medical University of South Carolina Charleston, SC, USA Carol Feghali-Bostwick, PhD Rheumatology and Immunology Medical University of South Carolina Charleston, SC, USA

Methods to Study Lung Injury and Repair.- Mouse Models of Acute Lung Injury.- Transgenic Animal Models in Lung Research.- Fundamental Methods for Analysis of Acute Lung Injury in Mice.- Invasive Measurement of Pulmonary Function in Mice.- Analysis of Epithelial Injury and Repair.- Flow Cytometric Evaluation of Acute Lung Injury and Repair.- Lung Imaging in Animal Models.- Genetic and Genomic Approaches to Acute Lung Injury.- MicroRNA Analysis in Acute Lung Injury.

lt;p>"Acute Lung Injury and Repair: Scientific Fundamentals and Methods was written to serve as a resource for those who want to further their understanding of the pathogenesis of ARDS. ... this book is a useful resource for clinicians who are interested in increasing their understanding of basic science research that is currently being conducted on acute lung injury/ARDS." (Jay Berger and Ellise Delphin, Anestesia & Analgesia, Vol. 125 (5), November, 2017)

"Basic scientists and clinician investigators with an interest in ARDS are an appropriate audience for this work, which features contributions from clinicians and basic scientists in pulmonary and critical care from academic institutions ... . This is an excellent introduction to work in an area of great interest to intensivists. Investigators needing to understand approaches to an important clinical problem and clinicians needing a better understanding of relevant experimental methods will enjoy and benefit from this book." (David J. Dries, Doody's Book Reviews, January, 2017)

Erscheinungsdatum	26.11.2016
Reihe/Serie	Respiratory Medicine
Zusatzinfo	VIII, 185 p. 23 illus., 20 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Pneumologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Intensivmedizin
	Medizin / Pharmazie ► Studium
Schlagworte	ARDS • Bacterial Infections • Hyperoxia • Intensive Care Medicine • Intensive / Critical Care Medicine • LPS and bacterial pneumonia • Medicine • Pneumology/Respiratory System • Respiratory Medicine • transfusion-related acute lung injury • Ventilator-induced lung injury • Viral infections
ISBN-10	3-319-46525-2 / 3319465252
ISBN-13	978-3-319-46525-8 / 9783319465258
Zustand	Neuware