Advances and Controversies in Thalassemia Therapy: Bone Marrow Transplantation and Other Approaches

Examines the clinical features of thalassemia and current supportive and curative therapeutic strategies. Critically evaluates conventional therapies, followed by an up-to-date account of bone marrow transplantation, which is the only known cure for thalassemia. Contributors to this volume, who represent virtually all transplant centers involved in thalassemia, offer a wealth of case studies illustrating effective bone marrow transplantation. They also provide clinical guidelines for determining which patients are best suited for transplantation and discuss problems such as cyclosporine in children; patterns of graft rejection; infections; and change in growth and endocrine function.