Skin Stress Response Pathways
Springer International Publishing (Verlag)
978-3-319-43155-0 (ISBN)
As an Associate Professor, Pharmacology and Toxicology, College of Pharmacy, University of Arizona and President of the American Society for Photobiology (ASP; 2016-2018), Dr. Wondrak's research examines the pathological role of oxidative and proteotoxic stress in solar photodamage and skin cancer aiming at the design of novel molecular strategies for prevention and therapeutic intervention. http://www.pharmacy.arizona.edu/directory/georg-wondrak-phd
lt;p>Preface.
1. The skin lipidome under environmental stress - Technological platforms, molecular pathways and translational opportunities
2. Squalene and skin barrier function: From molecular target to biomarker of environmental exposure
3. Sunlight-induced DNA damage: molecular mechanisms and photoprotection strategies
4. Urocanic Acid and Skin Photodamage: New Light on an Old Chromophore
5. The Skin Extracellular Matrix as a Target of Environmental Exposure: Molecular Mechanisms, Prevention and Repair
6. Nitric Oxide Derivatives and Skin Environmental Exposure to light: From Molecular Pathways to Therapeutic Opportunities
7. Melanocortin 1 receptor (MC1R) as a global regulator of cutaneous UV responses: molecular interactions and opportunities for melanoma prevention8. The Cutaneous Melanocyte as a Target of Environmental Stressors: Molecular Mechanisms and Opportunities
9. The Role of Epidermal p38 Signaling in Solar UV Radiation-induced Inflammation: Molecular Pathways and Preventive Opportunities
10. UV-Induced Chemokines as Emerging Targets for Skin Cancer Photochemoprevention11. TLR3 and Inflammatory Skin Diseases: From Environmental Factors to Molecular Opportunities
12. Sirtuins and stress response in skin cancer, aging, and barrier function
13. Cutaneous Opioid Receptors and Stress Responses: Molecular Interactions and Opportunities for Therapeutic Intervention
14. Regulation of Cutaneous Stress Response Pathways by the Circadian Clock: From Molecular Pathways to Therapeutic Opportunities
15. Endocannabinoids and Skin Barrier Function: Molecular Pathways and Therapeutic Opportunities
16. The aryl hydrocarbon receptor (AhR) as an environmental stress sensor and regulator of skin barrier function: Molecular mechanisms and therapeutic opportunities
17. Biological cell protection by natural compounds, a second line of defense against solar radiation
18. The Cutaneous Microbiota as a Determinant of Skin Barrier Function: Molecular Interactions and Therapeutic Opportunities
19. Sensing Environmental Factors: The Emerging Role of Receptors in Epidermal Homeostasis and Whole-Body Health
20. The Cutaneous Circadian Clock as a Determinant of Environmental Vulnerability: Molecular Pathways and Chrono-pharmacological Opportunities
21. Psychological stress as a determinant of skin barrier function: Immunological pathways and therapeutic opportunities
Index
Erscheinungsdatum | 08.10.2016 |
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Zusatzinfo | IX, 457 p. 68 illus., 39 illus. in color. |
Verlagsort | Cham |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Medizin / Pharmazie ► Studium |
Schlagworte | Biomedical and Life Sciences • Biomedicine general • Environmental Exposure • Skin Barrier Function • skin health • small molecule intervention strengthening skin fun • small molecule intervention strengthening skin function • stress response signaling |
ISBN-10 | 3-319-43155-2 / 3319431552 |
ISBN-13 | 978-3-319-43155-0 / 9783319431550 |
Zustand | Neuware |
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