The Art, Science, and Technology of Pharmaceutical Compounding - Loyd V. Allen

The Art, Science, and Technology of Pharmaceutical Compounding

(Autor)

Buch | Hardcover
650 Seiten
2016 | Fifth Edition
American Pharmacists Association (Verlag)
978-1-58212-263-2 (ISBN)
128,40 inkl. MwSt
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Presents in a logical and progressive format all the information that pharmacists and student pharmacists need to understand the purpose and processes of compounding. Loyd Allen covers basic guidelines, economic and technical factors that compounding pharmacists must consider, and all aspects of manufacturing practices for compounded medications.
The Art, Science, and Technology of Pharmaceutical Compounding presents in a logical and progressive format all the information that pharmacists and student pharmacists need to understand the purpose and processes of compounding. Author Loyd V. Allen Jr., the preeminent expert, covers basic guidelines, economic and technical factors that compounding pharmacists must consider, and all aspects of good manufacturing practices for compounded medications. In this fth edition, all chapters have been updated and several signicantly revised—particularly “Compounding with Hazardous Drugs”—and three new chapters have been added: “Pharmaceutical Compounding Errors,” “Foams,” and “Compounding with Special Ingredients.” Information on the new law affecting compounding, the Drug Quality and Security Act, is incorporated throughout the book. Chapter 14 now includes information on compounding “ lms.”

Key Features:

The initial chapters describe the requisite facilities and equipment, record keeping, calculations, and quality control.
Three new chapters: “Pharmaceutical Compounding Errors,” “Foams,” and “Compounding with Special Ingredients.”
Fifteen chapters are devoted to the compounding of each dosage form in turn, from
powders and granules to injectables.
Additional chapters cover veterinary compounding, compounding for special populations,
compounding for speci c procedures, compounding for clinical studies, compounding
cosmetics, compounding with hazardous drugs, and compounding in the event of a natural
disaster or terrorist attack.
Nine appendices provide essential information on the compounding process and
examples of standard operating procedures.
The necessary ingredients and steps are listed for compounding more than 200 sample
formulations, including bases, vehicles, and ingredient-speci c preparations.
Updated throughout, including information on the new Drug Quality and Security Act.

Loyd V. Allen, Jr. PhD, is Editorin- Chief, International Journal of Pharmaceutical Compounding and Remington: The Science and Practice of Pharmacy, and Professor Emeritus, College of Pharmacy, University of Oklahoma, Oklahoma City.

Preface
Introduction
Abbreviations and Approximate Solubility
Descriptors
1. Laws, Regulations, Standards and
Guidelines for Compounding
Practices
2. Compounding Ingredient
Considerations
3. Compounding with Hazardous Drugs
4. Facilities, Equipment, and Supplies
5. Records and Record Keeping
6. Stability of Compounded
Preparations
7. Pharmaceutical Compounding
Calculations
8. Quality Control
9. Flavors, Sweeteners, and Colors
10. Preservation, Sterilization, and
Depyrogenation
11. Powders and Granules
12. Capsules
13. Tablets
14. Lozenges, Troches, and Films
15. Suppositories and Inserts
16. Sticks
17. Solutions
18. Suspensions
19. Emulsions
20. Foams
21. Ointments, Creams, and Pastes
22. Gels
23. Ophthalmic, Otic, and Nasal
Preparations
24. Inhalation Preparations
25. Parenteral Preparations
26. Biotechnology, Nanotechnology, and
Pharmacogenomics
27. Special Populations and Preparations
28. Compounding with Special
Ingredients
29. Veterinary Pharmaceuticals
30. Compounding for Clinical and
Investigational Studies
31. Cosmetics for Special Populations
and for Use as Vehicles
32. Compounding for Terrorist Attacks
and Natural Disasters
33. Pharmaceutical Compounding Errors
Appendix I – Drugs and Dosage Forms
Not to be Compounded (The FDA
Negative List)
Appendix II – Standard Operating
Procedures
Appendix III – Speci c Gravity Values of
Selected Liquids
Appendix IV – Using Weight-Related
Conversion Factors
Appendix V – Sodium Chloride Equivalent
Values of Selected Agents
Appendix VI – Buffers and Buffer Solutions
Appendix VII – Compendial Requirements
for Bacterial Endotoxins in Sterile
Preparations
Appendix VIII – Viscosity-Increasing Agents
for Aqueous and Nonaqueous Systems
Appendix IX – Disinfecting Agents Used in
Compounding Pharmacies
Index

Erscheinungsdatum
Verlagsort Washington
Sprache englisch
Maße 178 x 254 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pflege
Medizin / Pharmazie Pharmazie PTA / PKA
ISBN-10 1-58212-263-6 / 1582122636
ISBN-13 978-1-58212-263-2 / 9781582122632
Zustand Neuware
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