Neonatal Seizures

Professor Lakshmi Nagarajan is Consultant Neurologist/Epileptologist and Head of the Department of Neurology at the Princess Margaret Hospital for Children, Perth, Western Australia. She also runs the Comprehensive Epilepsy Programme for Children and Adolescents in Western Australia. Her research interests include neonatal seizures, childhood epilepsy, paediatric neurology and clinical neurophysiology. Prof Nagarajan is a member of the Board of Directors of the International Child Neurology Association and the Australian New Zealand Child Neurology Society. She has published close to 50 papers in peer reviewed journals.

AUTHORS' APPOINTMENTS vii FOREWORD x PREFACE xii ACKNOWLEDGEMENTS xiii 1. DEVELOPMENT OF THE NEONATAL CEREBRAL CORTEX 1 Soumya Ghosh 2. THE ROLE OF THE VIDEO EEG IN NEONATES WITH SEIZURES 12 Lakshmi Nagarajan and Soumya Ghosh 3. RECORDING A VIDEO-EEG STUDY IN A NEONATE 30 Linda Palumbo and Lakshmi Nagarajan 4. THE ROLE OF AMPLITUDE-INTEGRATED EEG IN THE MANAGEMENT OF NEONATAL SEIZURES 40 Lena Hellstrom-Westas, Ingmar Rosen and Linda S. de Vries 5. ADVANCES IN NEUROPHYSIOLOGY AND NEONATAL SEIZURES: AUTOMATED SEIZURE DETECTION 56 Nathan J. Stevenson and Geraldine B. Boylan 6. NEUROIMAGING IN NEONATAL SEIZURES 76 Camilo Jaimes, Christos Papadelis and P. Ellen Grant 7. NEONATAL EPILEPSIES AND EPILEPTIC ENCEPHALOPATHIES 100 Maria Roberta Cilio 8. CLINICAL APPROACH TO A NEONATE WITH SEIZURES 114 Shripada Rao, Barry Lewis, Soumya Ghosh and Lakshmi Nagarajan 9. TREATMENT OF NEONATAL SEIZURES 128 Lakshmi Nagarajan 10. PREDICTORS OF NEURODEVELOPMENTAL OUTCOME IN INFANTS WITH NEONATAL SEIZURES 146 Lakshmi Nagarajan, Andrea Poretti, Thierry A G M Huisman and Soumya Ghosh 11. NEURODEVELOPMENTAL OUTCOMES OF NEONATES WITH SEIZURES 163 Jarred Garfinkle and Michael I Shevell 12. NEUROPROTECTIVE STRATEGIES FOR NEONATES WITH SEIZURES 172 Shilpa D. Kadam, Xiaohe Yu and Michael V. Johnston INDEX 193