HIV-associated Hematological Malignancies (eBook)

This book presents a general introduction to and review of HIV-associated hematological malignancies, with a special focus on practical management issues. Each of the relevant malignancies is addressed individually, with an overview of treatment approaches, assessment of evidence regarding their efficacy, and discussion of therapeutic controversies. In addition, careful consideration is paid to issues in molecular and clinical pathology, epidemiological aspects, symptomatology, diagnosis, and risk factors. Separate chapters are devoted to autologous and allogeneic stem cell transplantation and to chemotherapy and interactions with antiretroviral agents. Many of the chapters are written by experts who have been instrumental in shifting the balance for people living with HIV and blood cancers. While two decades ago this diagnosis represented a death sentence, advances in treatment have transformed these cancers into often curable conditions. Nevertheless, optimal treatment of hematological malignancies remains a challenge, particularly in patients with severe immunosuppression. This book will be an invaluable source of information for all practitioners in the fields of clinical hematology and medical oncology and HIV medicine.

Marcus Hentrich is an Associate Professor of Medicine at the Ludwig Maximilian University of Munich and head of the Department of Medicine III at Redcross Hospital Munich. Dr Hentrich received his medical degree from Technical University of Munich and was trained in Internal Medicine at Academic Teaching Hospitals in Munich. He is board certified in Hematology and Medical Oncology. In his current position he is director of the stem cell transplant unit at Redcross Hospital Munich. He's especially interested in HIV-related malignancies with a special focus on malignant lymphoma and testis cancer. In 2013 Dr. Hentrich was awarded the German AIDS Prize of the German AIDS Society. He is Deputy Chairman of the leukemia and lymphoma task force of the Munich Tumor Center and of the Stem Cell Transplantation Working Group Munich. Dr. Hentrich has conducted novel investigations on HIV-related lymphoma and infectious complications in hematologic malignancies.

Stefan K. Barta is an Assistant Professor of Medicine at the Fox Chase Cancer Center/Temple University Health System in Philadelphia, USA.

Dr Barta received his medical degree from the Johann-Wolfgang Goethe University in Frankfurt/Main, Germany. After Internal Medicine training in the United Kingdom, he underwent specialty training in Hematology and Oncology at the Montefiore Medical Center/Albert-Einstein College of Medicine in the Bronx, NY. There, he also completed a Master's degree in Clinical Research Methodology. He currently works at the Fox Chase Cancer Center, where he specializes in lymphoid malignancies. His research interests include HIV-related and other virally mediated lymphomas. He is an active member of the AIDS Malignancy Consortium Lymphoma Working Group and the ECOG Lymphoma Core Committee. His research has been recognized with an American Society of Clinical Oncology Young Investigator Award and an ECOG-ACRIN Young Investigator Symposium Award of Distinction for Clinical Research.