Mouse Models for Drug Discovery

Genetically Defined Strains in Drug
Development and Toxicity Testing.- Simple, Efficient CRISPR-Cas9
Mediated Gene Editing in Mice: Strategies and Methods.- Mouse Sperm Cryopreservation and
Recovery of Genetically Modified Mice.- Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment
of Hematopoietic Stem Cells.- Generation of Human Liver Chimeric
Mice for the Study of Human Hepatotropic Pathogens.- Human FcRn Transgenic Mice for
Pharmacokinetic Evaluation of Therapeutic Antibodies.- A Humanized Mouse Model to Study
Human Albumin and Albumin Conjugates Pharmacokinetics.- Germ-Free Mice Model for Studying
Host-Microbial Interactions.- Bridging Mice to Men: Using HLA
Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune
Type 1 Diabetes in Humans.- Mouse Models of Type 2 Diabetes
Mellitus in Drug Discovery.- Cholesterol Absorption and
Metabolism.- Skin Diseases in Laboratory Mice:
Approaches to Drug Target Identification and Efficacy Screening.- Chronic Myeloid Leukemia (CML) Mouse
Model in Translational Research.- Murine Model for Colitis-Associated
Cancer of the Colon.- Mouse Models for Studying
Depression-Like States and Antidepressant Drugs.- Experimental Models of Anxiety for
Drug Discovery and Brain Research.- Repetitive Behavioral Assessments
for Compound Screening in Mouse Models of Autism Spectrum Disorders.- Better Utilization of Mouse Models
of Neurodegenerative Diseases in Preclinical Studies: From the Bench to the
Clinic.- Neuromuscular Disease Models and
Analysis.- Brightfield Imaging and Optical Coherence Tomography of the Mouse
Posterior Eye.- Mouse
Models as Tools to Identify Genetic Pathways for Retinal Degeneration, as
Exemplified by Leber's Congenital Amaurosis.