The Major Histocompatibility Complex

The Major Histocompatibility Complex (or Human Leukocyte Antigen - HLA - in humans), a four-megabase segment of the human genome, contains key elements of the adaptive immune system. This book covers the complex in three sections. The first section deals with the historical background and basic science of the complex. The second section reviews the clinical aspects, such as transplantation, infectious diseases and tumor biology. The book concludes with a focus on laboratory science such as typing and assays.