Epitope Recognition Since Landsteiner’s Discovery

100 Years Since the Discovery of Human Blood Groups

M. Eibl, W.R. Mayr, G.J. Thorbecke (Herausgeber)

Buch | Softcover

XX, 120 Seiten

2002 | 2002
Springer Berlin (Verlag)
978-3-540-42651-6 (ISBN)

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Karl Landsteiner is best known for his discovery of the human blood goups. The revolutionary discoveries of this brilliant scientist in other fields have not received the recognition they deserve. His demonstration that poliomyelitis is transmissable showed the way of modern virology. His studies opening the field for epitope recognition, which he himself considered his main achievement, laid the foundation for research ongoing in our days. This book with its outstanding contributors is but a small tribute to this visionary scientist.

Introduction.-Landsteiner in Vienna.-Antigen Recognition: 100 years after Landsteiner.-Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: Enhanced in vivo potency of encephalitogenic peptides.-Determination of the expresssed T cell repertoire: The outcome of competition at the levels of antigen presentation and T cell receptor recognition.-Using monoclonal antibodies and site directed mutagenesis to map the epitopes of the blood group Rh D antigen.-Infections and the immune response to cardiac antigens.-Subject index

Erscheint lt. Verlag	11.4.2002
Zusatzinfo	XX, 120 p. 35 illus., 7 illus. in color.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	287 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
Themenwelt	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
Schlagworte	Antigen • Antigen recognition • autoimmune disease • blood groups • Blutgruppen • immune response • Infections • monoclonal antibodies • T cell receptor
ISBN-10	3-540-42651-5 / 3540426515
ISBN-13	978-3-540-42651-6 / 9783540426516
Zustand	Neuware